Concepedia

T Cell Avidity

T Cell Avidity is the overall strength of interaction between a T cell and an antigen-presenting cell, determined by the combined affinities of T cell receptor–peptide/MHC complexes and co-stimulatory molecule interactions, that quantitatively reflects the functional sensitivity of a T cell to its cognate antigen.

298

Publications

23.7K

Citations

1.7K

Authors

466

Institutions

Publications per year

2017–2026

38

Parents

Publications

298

Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19

Takuya Sekine, André Perez‐Potti, Olga Rivera‐Ballesteros et al. · Cell · 2020 · 2K citations · Full text

, , +15

Direct observation of ligand recognition by T cells

Darrell J. Irvine, Marco A. Purbhoo, Michelle Krogsgaard et al. · Nature · 2002 · 822 citations

, , +16

Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

Martha A. Alexander‐Miller, Graham R. Leggatt, J A Berzofsky · Proceedings of the National Academy of Sciences · 1996 · 507 citations · Full text

, , +16

Low avidity recognition of self-antigen by T cells permits escape from central tolerance

George Y. Liu, Paul J. Fairchild, Richard Smith et al. · Immunity · 1995 · 414 citations · Full text

, , +15

Isolation of High Avidity Melanoma-Reactive CTL from Heterogeneous Populations Using Peptide-MHC Tetramers

Cassian Yee, Peter A. Savage, Peter P. Lee et al. · The Journal of Immunology · 1999 · 413 citations · Full text

, , +17

1–5 of 298

Authors

1.7K

  1. DE
    Daniel E. Speiser

    University of Lausanne, Switzerland

    14 publications · 1.2K citations

    13

    h-index

  2. PG
    Philippe Guillaume

    Ludwig Cancer Research, Switzerland

    10 publications · 895 citations

    10

    h-index

  3. PS
    Pere Santamaría

    University of Calgary, Canada

    9 publications · 868 citations

    9

    h-index

  4. JP
    Jonathan P. Schneck

    Johns Hopkins University, United States

    8 publications · 633 citations

    8

    h-index

  5. NR
    Nathalie Rufer

    University of Lausanne, Switzerland

    7 publications · 576 citations

    7

    h-index

1–5 of 1.7K

Institutions

466

  1. Ludwig Cancer Research

    Zurich, Switzerland

    17 h-index

    114 publications

    8.2K citations

  2. Inserm

    Paris, France

    16 h-index

    97 publications

    4.8K citations

  3. University of Lausanne

    Lausanne, Switzerland

    15 h-index

    115 publications

    6.3K citations

  4. National Institutes of Health

    Bethesda, United States

    15 h-index

    57 publications

    6.2K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    15 h-index

    41 publications

    9.1K citations

  6. Johns Hopkins University

    Baltimore, United States

    12 h-index

    53 publications

    6.3K citations

  7. National Cancer Institute

    Bethesda, United States

    11 h-index

    41 publications

    6.6K citations

  8. University of Washington

    Seattle, United States

    10 h-index

    25 publications

    3.4K citations

1–8 of 466

Venues

  1. The Journal of Immunology

    JI · 76 publications · 4.7K citations

    43

    h-index

  2. The Journal of Experimental Medicine

    18 publications · 3K citations

    18

    h-index

  3. European Journal of Immunology

    EJI · 20 publications · 790 citations

    16

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 11 publications · 1.4K citations

    11

    h-index

  5. Immunity

    9 publications · 1.6K citations

    9

    h-index

1–5