Philippe Guillaume

Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8+ T cell dysfunction in melanoma patients

Julien Fourcade, Zhaojun Sun, Mourad Benallaoua et al. · The Journal of Experimental Medicine · 2010 · 1.3K citations · Full text

Life Sciences, Immunology, Oncology +17

CD8+ T Cells Specific for Tumor Antigens Can Be Rendered Dysfunctional by the Tumor Microenvironment through Upregulation of the Inhibitory Receptors BTLA and PD-1

Julien Fourcade, Zhaojun Sun, Ornella Pagliano et al. · Cancer Research · 2011 · 366 citations · Full text

Life Sciences, Immunology, Oncology +17

Effector Function of Human Tumor-Specific CD8 T Cells in Melanoma Lesions: A State of Local Functional Tolerance

Alfred Zippelius, Pascal Batard, Verena Rubio‐Godoy et al. · Cancer Research · 2004 · 364 citations · Full text

Life Sciences, Immunology, Oncology +17

Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer

Amélie Cachot, Mariia Bilous, Yen‐Cheng Liu et al. · Science Advances · 2021 · 320 citations · Full text

Life Sciences, Immunology, Oncology +16

Robust prediction of HLA class II epitopes by deep motif deconvolution of immunopeptidomes

Julien Racle, Justine Michaux, Georg Alexander Rockinger et al. · Nature Biotechnology · 2019 · 305 citations

Life Sciences, Bioinformatics, Immunology +15