Alfred Zippelius

Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial

Tony Mok, Yi‐Long Wu, Iveta Kudaba et al. · The Lancet · 2019 · 3.3K citations · Full text

Medicine, Oncology, Pharmacology +15

A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade

Daniela S. Thommen, Viktor H. Koelzer, Petra Herzig et al. · Nature Medicine · 2018 · 1.2K citations · Full text

Life Sciences, Immunology, Oncology +16

RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types

Gianni Monaco, Bernett Lee, Weili Xu et al. · Cell Reports · 2019 · 1K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12

Christopher Garris, Sean P. Arlauckas, Rainer H. Köhler et al. · Immunity · 2018 · 937 citations · Full text

Medicine, Immunology, Oncology +12

CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors

Haiping Wang, Fabien Franco, Yao-Chen Tsui et al. · Nature Immunology · 2020 · 647 citations · Full text

Life Sciences, Biochemistry, Immunology +10