Daniela S. Thommen

A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade

Daniela S. Thommen, Viktor H. Koelzer, Petra Herzig et al. · Nature Medicine · 2018 · 1.2K citations · Full text

Life Sciences, Immunology, Oncology +16

Progression of Lung Cancer Is Associated with Increased Dysfunction of T Cells Defined by Coexpression of Multiple Inhibitory Receptors

Daniela S. Thommen, Jens Schreiner, Philipp Müller et al. · Cancer Immunology Research · 2015 · 381 citations

Life Sciences, Immunology, Oncology +17

An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer

Paula Voabil, Marjolein de Bruijn, Lisanne M. Roelofsen et al. · Nature Medicine · 2021 · 369 citations

Medicine, Cancer Biology, Oncology +14

Trastuzumab emtansine (T-DM1) renders HER2 ⁺ breast cancer highly susceptible to CTLA-4/PD-1 blockade

Philipp Müller, Matthias Kreuzaler, Tarik A. Khan et al. · Science Translational Medicine · 2015 · 335 citations

Medicine, Oncology, Pharmacology +17

Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells

Michal A. Stanczak, Shoib Sarwar Siddiqui, Marcel P. Trefny et al. · Journal of Clinical Investigation · 2018 · 306 citations · Full text

Life Sciences, Immunology, Oncology +17