Trastuzumab emtansine (T-DM1) renders HER2 ⁺ breast cancer highly susceptible to CTLA-4/PD-1 blockade

Philipp Müller, Matthias Kreuzaler, Tarik A. Khan, +12

Science Translational Medicine

Breast OncologyImmunologyRegulatory T CellsCell PolarizationImmunotherapeutics +15

Concentrated Dispersions of Equilibrium Protein Nanoclusters That Reversibly Dissociate into Active Monomers

Keith P. Johnston, Jennifer A. Maynard, Thomas M. Truskett, +6

ACS Nano

NanoparticlesEquilibrium Protein NanoclustersNanotherapeuticsEngineeringNanocluster +21

Accurate and predictive antibody repertoire profiling by molecular amplification fingerprinting

Tarik A. Khan, Simon Friedensohn, Arthur R. Gorter de Vries, +3

Science Advances

In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSe_<i>x</i>S_2–<i>x</i>)/ZnS Core/Shell Quantum Dots

Matthew G. Panthani, Tarik A. Khan, Dariya K. Reid, +4

Nano Letters

Quantitative assessment of the robustness of next-generation sequencing of antibody variable gene repertoires from immunized mice

Victor Greiff, Ulrike Menzel, Ulrike Haessler, +6

BMC Immunology

Comprehensive Evaluation and Optimization of Amplicon Library Preparation Methods for High-Throughput Antibody Sequencing

Ulrike Menzel, Victor Greiff, Tarik A. Khan, +6

PLoS ONE

EngineeringImmunologyMolecular BiologyHigh-throughput Antibody SequencingGenomics +23

Protein-Polydimethylsiloxane Particles in Liquid Vial Monoclonal Antibody Formulations Containing Poloxamer 188

Christoph Grapentin, Claudia Müller, Ravuri S. K. Kishore, +4

Journal of Pharmaceutical Sciences

EngineeringImmunologyBiomedical EngineeringProtein NanoparticlesPoloxamer 188 +17

Advancing Therapeutic Protein Discovery and Development through Comprehensive Computational and Biophysical Characterization

Lorenzo Gentiluomo, Hristo L. Svilenov, Dillen Augustijn, +23

Molecular Pharmaceutics

Therapeutic Protein DiscoveryBiomolecular Structure PredictionMolecular BiologyProtein FoldingBioanalysis +18

Convergent selection in antibody repertoires is revealed by deep learning

Simon Friedensohn, Daniel Neumeier, Tarik A. Khan, +6

EngineeringAdaptive Immune SystemArtificial Immune SystemImmunologyImmunodominance +22

Adsorption of non-ionic surfactant and monoclonal antibody on siliconized surface studied by neutron reflectometry

Zhenhuan Zhang, Ann Marie Woys, Kunlun Hong, +5

Journal of Colloid and Interface Science

Chemical EngineeringNon-ionic SurfactantEngineeringSurface FunctionalizationSurface Chemistry +7