Graham R. Leggatt

Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

Martha A. Alexander‐Miller, Graham R. Leggatt, J A Berzofsky · Proceedings of the National Academy of Sciences · 1996 · 506 citations

Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity

Purnima Bhat, Graham R. Leggatt, Nigel J. Waterhouse et al. · Cell Death and Disease · 2017 · 482 citations · Full text

Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL.

Martha A. Alexander‐Miller, Graham R. Leggatt, Apurva Sarin et al. · The Journal of Experimental Medicine · 1996 · 221 citations · Full text

T-regulatory Cell, Apoptosis, Immunology +17

Increased lipid metabolism impairs NK cell function and mediates adaptation to the lymphoma environment

T Kobayashi, Pui Yeng Lam, Hui Jiang et al. · Blood · 2020 · 166 citations · Full text

Antigen-specific CD4+ T-cell help is required to activate a memory CD8+ T cell to a fully functional tumor killer cell.

Feng Gao, Vithagna Khammanivong, Wen Jun Liu et al. · PubMed · 2002 · 149 citations

Adaptive Immune System, Immunology, Antigen Processing +16