Concepedia

Structure-based Functional Annotation

Structure-Based Functional Annotation is a computational method in structural bioinformatics that assigns biological function to a macromolecule based on its three-dimensional structure, distinguishing it from sequence-based approaches by relying on structural homology, active site geometry, and molecular surface properties.

219

Publications

28.4K

Citations

972

Authors

358

Institutions

Publications per year

2017–2026

52

Parents

Children

Publications

219

The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

Damian Szklarczyk, Andrea Franceschini, Michael Kuhn et al. · Nucleic Acids Research · 2010 · 3.6K citations · Full text

, , +17

CDD: a Conserved Domain Database for the functional annotation of proteins

Aron Marchler‐Bauer, Shuo Lu, J. B. Anderson et al. · Nucleic Acids Research · 2010 · 3.2K citations · Full text

, , +15

I-TASSER server: new development for protein structure and function predictions

Jianyi Yang, Yang Zhang · Nucleic Acids Research · 2015 · 2.7K citations · Full text

, , +16

CASTp: computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues

Joseph Dundas, Zhengbiao Ouyang, Jeng‐Sen Tseng et al. · Nucleic Acids Research · 2006 · 1.7K citations · Full text

, , +16

COFACTOR: an accurate comparative algorithm for structure-based protein function annotation

Ambrish Roy, Jianyi Yang, Yang Zhang · Nucleic Acids Research · 2012 · 731 citations · Full text

, , +17

1–5 of 219

Authors

972

  1. JM
    Janet M. Thornton

    University College London, United Kingdom

    11 publications · 1.3K citations

    11

    h-index

  2. CO
    Christine Orengo

    University College London, United Kingdom

    11 publications · 1.2K citations

    11

    h-index

  3. RB
    Russ B. Altman

    Stanford University, United States

    8 publications · 574 citations

    8

    h-index

  4. YZ
    Yang Zhang

    University of Michigan, United States

    7 publications · 4.9K citations

    7

    h-index

  5. OL
    Olivier Lichtarge

    Baylor College of Medicine, United States

    7 publications · 352 citations

    7

    h-index

1–5 of 972

Institutions

358

  1. European Bioinformatics Institute

    Cambridge, United Kingdom

    13 h-index

    34 publications

    6.1K citations

  2. University College London

    London, United Kingdom

    12 h-index

    65 publications

    7.1K citations

  3. Institute of Structural and Molecular Biology

    London, United Kingdom

    10 h-index

    47 publications

    7.5K citations

  4. Wellcome Trust

    London, United Kingdom

    9 h-index

    16 publications

    2.5K citations

  5. Stanford University

    Stanford, United States

    9 h-index

    22 publications

    2K citations

  6. University of Michigan

    Ann Arbor, United States

    8 h-index

    25 publications

    12K citations

  7. Baylor College of Medicine

    Houston, United States

    7 h-index

    38 publications

    1.9K citations

  8. Georgia Institute of Technology

    Atlanta, United States

    7 h-index

    20 publications

    1.3K citations

1–8 of 358

Venues

  1. Nucleic Acids Research

    38 publications · 17.1K citations

    33

    h-index

  2. BMC Bioinformatics

    13 publications · 418 citations

    13

    h-index

  3. Proteins Structure Function and Bioinformatics

    14 publications · 839 citations

    12

    h-index

  4. Bioinformatics

    13 publications · 848 citations

    12

    h-index

  5. Protein Science

    PS · 10 publications · 562 citations

    10

    h-index

1–5