Concepedia

Enzyme Function Classification

Enzyme Function Classification is a computational method within structure-based functional annotation that discriminates enzymatic activities by predicting specific functional classes from three-dimensional protein structures, distinguished from sequence-based approaches through its reliance on structural motifs and active site geometry.

151

Publications

14.1K

Citations

624

Authors

244

Institutions

Publications per year

2017–2026

43

Parents

Publications

151

A classification of glycosyl hydrolases based on amino acid sequence similarities

Bernard Henrissat · Biochemical Journal · 1991 · 3.2K citations · Full text

, , +12

HydDB: A web tool for hydrogenase classification and analysis

Dan Søndergaard, Christian N. S. Pedersen, Chris Greening · Scientific Reports · 2016 · 570 citations · Full text

, , +15

Designed divergent evolution of enzyme function

Yasuo Yoshikuni, Thomas E. Ferrin, Jay D. Keasling · Nature · 2006 · 442 citations

, , +11

BRENDA in 2013: integrated reactions, kinetic data, enzyme function data, improved disease classification: new options and contents in BRENDA

Ida Schomburg, Antje Chang, Sandra Placzek et al. · Nucleic Acids Research · 2012 · 426 citations · Full text

, , +17

The relationship between protein structure and function: a comprehensive survey with application to the yeast genome

Hédi Hegyi, Mark Gerstein · Journal of Molecular Biology · 1999 · 425 citations · Full text

, , +17

1–5 of 151

Authors

624

  1. JM
    Janet M. Thornton

    University College London, United Kingdom

    7 publications · 761 citations

    7

    h-index

  2. PC
    Patricia C. Babbitt

    University of California, San Francisco, United States

    5 publications · 385 citations

    5

    h-index

  3. DS
    Dietmar Schomburg

    Technische Universität Braunschweig, Germany

    5 publications · 1.2K citations

    5

    h-index

  4. RA
    Roman A. Laskowski

    European Bioinformatics Institute, United Kingdom

    3 publications · 410 citations

    3

    h-index

  5. SA
    Syed Asad Rahman

    European Bioinformatics Institute, United Kingdom

    3 publications · 101 citations

    3

    h-index

1–5 of 624

Institutions

244

  1. European Bioinformatics Institute

    Cambridge, United Kingdom

    8 h-index

    36 publications

    2.8K citations

  2. Technische Universität Braunschweig

    Braunschweig, Germany

    5 h-index

    31 publications

    10.4K citations

  3. University of Minnesota

    Minneapolis, United States

    4 h-index

    15 publications

    1.8K citations

  4. University College London

    London, United Kingdom

    4 h-index

    15 publications

    1.4K citations

  5. Wellcome Trust

    London, United Kingdom

    4 h-index

    16 publications

    1.9K citations

  6. University of California, San Francisco

    San Francisco, United States

    4 h-index

    19 publications

    2.8K citations

  7. Technical University of Denmark

    Kongens Lyngby, Denmark

    3 h-index

    5 publications

    211 citations

  8. University of Illinois Urbana-Champaign

    Urbana, United States

    3 h-index

    14 publications

    1.2K citations

1–8 of 244

Venues

  1. BMC Bioinformatics

    10 publications · 537 citations

    10

    h-index

  2. Nucleic Acids Research

    9 publications · 1.8K citations

    9

    h-index

  3. Journal of Biological Chemistry

    JBC · 6 publications · 204 citations

    6

    h-index

  4. Bioinformatics

    6 publications · 499 citations

    6

    h-index

  5. PLoS Computational Biology

    5 publications · 261 citations

    5

    h-index

1–5