Concepedia

Binding Specificity Prediction

Binding Specificity Prediction is a computational method within structure-based functional annotation that identifies the precise molecular targets or ligands a biomolecule interacts with by analyzing its three-dimensional structure, distinguishing itself from general binding prediction approaches through its focus on specificity rather than mere interaction potential.

196

Publications

15.2K

Citations

855

Authors

297

Institutions

Publications per year

2017–2026

57

Parents

Publications

196

Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning

Babak Alipanahi, Andrew Delong, Matthew T. Weirauch et al. · Nature Biotechnology · 2015 · 3.2K citations

, , +16

A Specificity Map for the PDZ Domain Family

Raffi Tonikian, Yingnan Zhang, Stephen L. Sazinsky et al. · PLoS Biology · 2008 · 491 citations · Full text

, , +17

PDZ Domain Binding Selectivity Is Optimized Across the Mouse Proteome

Michael A. Stiffler, Jiunn R Chen, Viara Grantcharova et al. · Science · 2007 · 381 citations · Full text

, , +17

Deep learning-based prediction of the T cell receptor–antigen binding specificity

Tianshi Lu, Ze Zhang, James Zhu et al. · Nature Machine Intelligence · 2021 · 294 citations · Full text

, , +12

CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites

Peter Cimermančič, Patrick Weinkam, T.J. Rettenmaier et al. · Journal of Molecular Biology · 2016 · 286 citations

, , +12

1–5 of 196

Authors

855

  1. GD
    Gary D. Stormo

    Washington University in St. Louis, United States

    6 publications · 682 citations

    6

    h-index

  2. AS
    Alessandro Sette

    La Jolla Institute for Immunology, United States

    4 publications · 385 citations

    4

    h-index

  3. PB
    Philip Bradley

    Fred Hutch Cancer Center, United States

    4 publications · 231 citations

    4

    h-index

  4. DB
    David Baker

    University of Washington, United States

    4 publications · 231 citations

    4

    h-index

  5. TH
    Tingjun Hou

    Zhejiang University, China

    4 publications · 298 citations

    4

    h-index

1–5 of 855

Institutions

297

  1. University of California San Diego

    San Diego, United States

    10 h-index

    45 publications

    2.5K citations

  2. Chinese Academy of Sciences

    Beijing, China

    8 h-index

    26 publications

    1.6K citations

  3. Harvard University

    Cambridge, United States

    7 h-index

    29 publications

    3.7K citations

  4. University of Toronto

    Toronto, Canada

    7 h-index

    35 publications

    12.5K citations

  5. University of Washington

    Seattle, United States

    7 h-index

    58 publications

    2.9K citations

  6. Washington University in St. Louis

    St Louis, United States

    6 h-index

    14 publications

    1.6K citations

  7. University of Wisconsin–Madison

    Madison, United States

    6 h-index

    11 publications

    1.7K citations

  8. Technical University of Denmark

    Kongens Lyngby, Denmark

    6 h-index

    15 publications

    1.4K citations

1–8 of 297

Venues

  1. Nucleic Acids Research

    24 publications · 1.9K citations

    22

    h-index

  2. Bioinformatics

    18 publications · 947 citations

    16

    h-index

  3. PLoS Computational Biology

    10 publications · 890 citations

    10

    h-index

  4. BMC Bioinformatics

    9 publications · 313 citations

    9

    h-index

  5. PLoS ONE

    6 publications · 174 citations

    6

    h-index

1–5