Concepedia

Functionally Important Residue Mapping

Functionally Important Residue Mapping is a computational method in structure-based functional annotation that identifies and localizes specific amino acid residues within a protein structure that are critical for its biological activity, thereby distinguishing it from general residue annotation by focusing on functional mechanistic roles derived from structural context.

87

Publications

7.8K

Citations

383

Authors

159

Institutions

Publications per year

2017–2026

9

Parents

Publications

87

CASTp: computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues

Joseph Dundas, Zhengbiao Ouyang, Jeng‐Sen Tseng et al. · Nucleic Acids Research · 2006 · 1.7K citations · Full text

, , +16

ConSurf: Identification of Functional Regions in Proteinsby Surface-Mapping of Phylogenetic Information

Fabian Glaser, Tal Pupko, Inbal Paz et al. · Bioinformatics · 2002 · 1.3K citations

, , +13

A method to predict functional residues in proteins

Georg Casari, Chris Sander, Alfonso Valencia · Nature Structural & Molecular Biology · 1995 · 424 citations

, , +10

Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition

Tsuyoshi Tanabe, Mathias Chamaillard, Yasunori Ogura et al. · The EMBO Journal · 2004 · 364 citations · Full text

, , +14

Functional arginyl residues as NADH binding sites of alcohol dehydrogenases

Louis G. Lange, James Riordan, Bert L. Vallée · Biochemistry · 1974 · 222 citations

, , +12

1–5 of 87

Authors

383

  1. SD
    Sean D. Mooney

    Buck Institute for Research on Aging, United States

    2 publications · 100 citations

    2

    h-index

  2. OL
    Olivier Lichtarge

    Baylor College of Medicine, United States

    2 publications · 187 citations

    2

    h-index

  3. RJ
    Robert J. Brooker

    University of Minnesota, United States

    2 publications · 80 citations

    2

    h-index

  4. JR
    James Riordan

    Harvard University, United States

    2 publications · 418 citations

    2

    h-index

  5. AV
    Alfonso Valencia

    Spanish National Cancer Research Centre, Spain

    2 publications · 632 citations

    2

    h-index

1–5 of 383

Institutions

159

  1. Johns Hopkins University

    Baltimore, United States

    4 h-index

    15 publications

    892 citations

  2. Baylor College of Medicine

    Houston, United States

    3 h-index

    13 publications

    1.2K citations

  3. University of California San Diego

    San Diego, United States

    2 h-index

    2 publications

    376 citations

  4. University of Minnesota

    Minneapolis, United States

    2 h-index

    4 publications

    154 citations

  5. Yale University

    New Haven, United States

    2 h-index

    4 publications

    320 citations

  6. University of Guelph

    Guelph, Canada

    2 h-index

    4 publications

    121 citations

  7. University of Oxford

    Oxford, United Kingdom

    2 h-index

    5 publications

    215 citations

  8. University of Göttingen

    Göttingen, Germany

    2 h-index

    10 publications

    165 citations

1–8 of 159

Venues

  1. Journal of Biological Chemistry

    JBC · 11 publications · 455 citations

    11

    h-index

  2. Biochemistry

    9 publications · 579 citations

    9

    h-index

  3. Journal of Molecular Biology

    JMB · 8 publications · 1.1K citations

    8

    h-index

  4. BMC Bioinformatics

    5 publications · 136 citations

    5

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 173 citations

    4

    h-index

1–5