Concepedia

Single-cell Pathway Analysis

Single-Cell Pathway Analysis is a computational statistical method in network biology that infers differential activity of molecular pathways at single-cell resolution by assessing changes in the multivariate joint expression patterns of genes within predefined pathways across individual cells or conditions.

52

Publications

4.4K

Citations

402

Authors

171

Institutions

Publications per year

2017–2026

34

Variants

Pathway Network AnalysisSignaling Pathway Analysis

Parents

Children

Publications

52

Causal Protein-Signaling Networks Derived from Multiparameter Single-Cell Data

Karen Sachs, Omar D. Perez, Dana Pe’er et al. · Science · 2005 · 1.7K citations

, , +17

Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells

John G. Albeck, John M. Burke, Bree B. Aldridge et al. · Molecular Cell · 2008 · 383 citations · Full text

, , +16

CellCall: integrating paired ligand–receptor and transcription factor activities for cell–cell communication

Yang Zhang, Tianyuan Liu, Xuesong Hu et al. · Nucleic Acids Research · 2021 · 265 citations · Full text

, , +17

Identification of resistance pathways and therapeutic targets in relapsed multiple myeloma patients through single-cell sequencing

Yaël C. Cohen, Mor Zada, Shuang-Yin Wang et al. · Nature Medicine · 2021 · 246 citations · Full text

, , +17

Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing

Roy Drissen, Natalija Buza-Vidas, Petter Woll et al. · Nature Immunology · 2016 · 225 citations

, , +12

1–5 of 52

Authors

402

  1. AC
    Alessandra Cesano

    The Wistar Institute, United States

    5 publications · 170 citations

    5

    h-index

  2. SP
    Santosh Putta

    Nodality (United States), United States

    4 publications · 156 citations

    4

    h-index

  3. DB
    David B. Rosen

    University of California, San Francisco, United States

    3 publications · 110 citations

    3

    h-index

  4. UG
    Urte Gayko

    Amgen (United States), United States

    3 publications · 110 citations

    3

    h-index

  5. BL
    Brent Louie

    Nodality (United States), United States

    3 publications · 78 citations

    3

    h-index

1–5 of 402

Institutions

171

  1. Nodality (United States)

    South San Francisco, United States

    5 h-index

    34 publications

    1.3K citations

  2. Harvard University

    Cambridge, United States

    5 h-index

    18 publications

    11.1K citations

  3. Center for Systems Biology

    Boston, United States

    3 h-index

    13 publications

    2.2K citations

  4. University of Edinburgh

    Edinburgh, United Kingdom

    3 h-index

    18 publications

    1.4K citations

  5. Stanford University

    Stanford, United States

    3 h-index

    8 publications

    8.9K citations

  6. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    4 publications

    276 citations

  7. Shanghai Jiao Tong University

    Shanghai, China

    2 h-index

    12 publications

    458 citations

  8. University of California, San Francisco

    San Francisco, United States

    2 h-index

    8 publications

    551 citations

1–8 of 171

Venues

  1. Nature Communications

    2 publications · 128 citations

    2

    h-index

  2. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 2 publications · 40 citations

    2

    h-index

  3. PLoS Computational Biology

    2 publications · 38 citations

    2

    h-index

  4. Methods in molecular biology

    Book series · 2 publications · 67 citations

    2

    h-index

  5. Scientific Reports

    2 publications · 36 citations

    2

    h-index

1–5