Concepedia

Pathway Activity Profiling

Pathway Activity Profiling is a computational method within single-cell pathway analysis that quantifies the functional activation states of biological pathways at single-cell resolution by integrating transcriptomic data with prior pathway knowledge to infer cell-specific pathway activities.

124

Publications

25.4K

Citations

1.6K

Authors

332

Institutions

Publications per year

2017–2026

64

Parents

Publications

124

GSVA: gene set variation analysis for microarray and RNA-Seq data

Sonja Hänzelmann, Robert Castelo, Justin Guinney · BMC Bioinformatics · 2013 · 16.5K citations · Full text

, , +17

Perturbation-response genes reveal signaling footprints in cancer gene expression

Michaël Schubert, Bertram Klinger, Martina Klünemann et al. · Nature Communications · 2017 · 1.1K citations · Full text

, , +17

Inferring Pathway Activity toward Precise Disease Classification

Eunjung Lee, Han‐Yu Chuang, Jong‐Won Kim et al. · PLoS Computational Biology · 2008 · 621 citations · Full text

, , +16

Pathway level analysis of gene expression using singular value decomposition

John K. Tomfohr, Jun Lü, Thomas B. Kepler · BMC Bioinformatics · 2005 · 450 citations · Full text

, , +10

Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data

Christian H. Holland, Jovan Tanevski, Javier Perales-Patón et al. · Genome biology · 2020 · 354 citations · Full text

, , +17

1–5 of 124

Authors

1.6K

  1. AV
    Anja van de Stolpe

    Philips (Netherlands), Netherlands

    4 publications · 150 citations

    4

    h-index

  2. JS
    Julio Sáez-Rodríguez

    Heidelberg University, Germany

    4 publications · 1.6K citations

    4

    h-index

  3. MA
    Márcia A. Inda

    Philips (Netherlands), Netherlands

    3 publications · 118 citations

    3

    h-index

  4. AH
    Andrea H. Bild

    University of Utah, United States

    3 publications · 107 citations

    3

    h-index

  5. WV
    Wim Verhaegh

    Philips (Netherlands), Netherlands

    3 publications · 125 citations

    3

    h-index

1–5 of 1.6K

Institutions

332

  1. Heidelberg University

    Heidelberg, Germany

    5 h-index

    11 publications

    2.4K citations

  2. Joint Research Centre

    Karlsruhe, Germany

    4 h-index

    5 publications

    2K citations

  3. Broad Institute

    Cambridge, United States

    4 h-index

    16 publications

    1.9K citations

  4. RWTH Aachen University

    Aachen, Germany

    4 h-index

    5 publications

    2K citations

  5. Philips (Netherlands)

    Amsterdam, The Netherlands

    4 h-index

    14 publications

    578 citations

  6. University of Miami

    Coral Gables, United States

    4 h-index

    7 publications

    257 citations

  7. European Bioinformatics Institute

    Cambridge, United Kingdom

    3 h-index

    5 publications

    2.8K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    5 publications

    120 citations

1–8 of 332

Venues

  1. BMC Bioinformatics

    7 publications · 17.1K citations

    7

    h-index

  2. Nature Communications

    5 publications · 1.6K citations

    5

    h-index

  3. PLoS ONE

    4 publications · 145 citations

    4

    h-index

  4. Journal of Proteome Research

    JPR · 3 publications · 115 citations

    3

    h-index

  5. Oncotarget

    3 publications · 141 citations

    3

    h-index

1–5