Concepedia

Pathway Deregulation Analysis

Pathway Deregulation Analysis is a computational method that identifies aberrant biological pathways in individual cells by quantifying deviations in pathway activity from a reference normative state, enabling the detection of dysregulated cellular functions in single-cell transcriptomic data.

32

Publications

1.8K

Citations

210

Authors

107

Institutions

Publications per year

2017–2026

13

Parents

Publications

32

Pathway-based personalized analysis of cancer

Yotam Drier, Michal Sheffer, Eytan Domany · Proceedings of the National Academy of Sciences · 2013 · 364 citations · Full text

, , +17

An integer linear programming approach for finding deregulated subgraphs in regulatory networks

Christina Backes, Alexander Rurainski, Gunnar W. Klau et al. · Nucleic Acids Research · 2011 · 261 citations · Full text

, , +14

Alveolar epithelial cell type II as main target of SARS-CoV-2 virus and COVID-19 development via NF-Kb pathway deregulation: A physio-pathological theory

Maurizio Carcaterra, C. Caruso · Medical Hypotheses · 2020 · 123 citations · Full text

, , +16

Age-Specific Differences in Oncogenic Pathway Deregulation Seen in Human Breast Tumors

Carey K. Anders, Chaitanya R. Acharya, David S. Hsu et al. · PLoS ONE · 2008 · 111 citations · Full text

, , +17

An integration of complementary strategies for gene-expression analysis to reveal novel therapeutic opportunities for breast cancer

Andrea H. Bild, Joel S. Parker, Adam M Gustafson et al. · Breast Cancer Research · 2009 · 75 citations · Full text

, , +17

1–5 of 32

Authors

210

  1. AK
    Andreas Keller

    Saarland University, Germany

    3 publications · 343 citations

    3

    h-index

  2. EM
    Eckart Meese

    Saarland University, Germany

    3 publications · 343 citations

    3

    h-index

  3. HL
    Hans‐Peter Lenhof

    Saarland University, Germany

    3 publications · 343 citations

    3

    h-index

  4. CB
    Christina Backes

    Saarland University, Germany

    3 publications · 343 citations

    3

    h-index

  5. YA
    Yves A. Lussier

    University of Chicago, United States

    2 publications · 56 citations

    2

    h-index

1–5 of 210

Institutions

107

  1. Saarland University

    Saarbrücken, Germany

    3 h-index

    16 publications

    863 citations

  2. Weizmann Institute of Science

    Rehovot, Israel

    2 h-index

    6 publications

    1.2K citations

  3. Duke Medical Center

    Durham, United States

    2 h-index

    12 publications

    1.1K citations

  4. Heidelberg University

    Heidelberg, Germany

    2 h-index

    22 publications

    1.5K citations

  5. University of Tübingen

    Tübingen, Germany

    2 h-index

    9 publications

    422 citations

  6. College of New Jersey

    Ewing, United States

    1 h-index

    1 publications

    18 citations

  7. Ospedale di Belcolle

    Viterbo, Italy

    1 h-index

    1 publications

    123 citations

  8. Alacris (Germany)

    Berlin, Germany

    1 h-index

    1 publications

    19 citations

1–8 of 107

Venues

  1. Bioinformatics

    5 publications · 201 citations

    5

    h-index

  2. npj Systems Biology and Applications

    3 publications · 57 citations

    3

    h-index

  3. PLoS ONE

    2 publications · 130 citations

    2

    h-index

  4. BMC Medical Genomics

    2 publications · 95 citations

    2

    h-index

  5. International Journal of Molecular Medicine

    1 publications · 24 citations

    1

    h-index

1–5