Concepedia

Semi-random Mutagenesis

Semi-Random Mutagenesis is a mutagenesis technique that introduces targeted nucleotide variations at specific sites within a gene sequence while retaining a degree of randomness in the choice of substituted amino acids, thereby combining the precision of site-directed mutagenesis with the diversity-generating capacity of random mutagenesis.

31

Publications

2.2K

Citations

160

Authors

61

Institutions

Publications per year

2017–2026

4

Parents

Publications

31

Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin.

Kurt R. Klimpel, Sean S. Molloy, Gary Thomas et al. · Proceedings of the National Academy of Sciences · 1992 · 459 citations

, , +17

Directed evolution of green fluorescent protein by a new versatile PCR strategy for site-directed and semi-random mutagenesis

Nucleic Acids Research · 2000 · 352 citations · Full text

, , +17

Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killing.

Margaret E. Black, Mark Kokoris, Peter J. Sabo · PubMed · 2001 · 158 citations

, , +13

<i>Streptococcus mutans</i> Strains Harboring Collagen-binding Adhesin

Yutaka Satō, Kazuko Okamoto, Akiyoshi Kagami et al. · Journal of Dental Research · 2004 · 124 citations

, , +13

Aryl Sulfonamides Degrade RBM39 and RBM23 by Recruitment to CRL4-DCAF15

Tabitha C. Ting, Maria Goralski, Katherine Klein et al. · Cell Reports · 2019 · 121 citations · Full text

, , +13

1–5 of 31

Authors

160

  1. GE
    Georg E. Schulz

    University of Freiburg, Germany

    1 publications · 96 citations

    1

    h-index

  2. MK
    Masashi Kurimoto

    Hayashibara (Japan), Japan

    1 publications · 10 citations

    1

    h-index

  3. KK
    Kyoko Kijima

    Kyoto University, Japan

    1 publications · 12 citations

    1

    h-index

  4. GR
    Geoffrey R. Moore

    University of East Anglia, United Kingdom

    1 publications · 83 citations

    1

    h-index

  5. MK
    Mario Kuttke

    Medical University of Vienna, Austria

    1 publications · 24 citations

    1

    h-index

1–5 of 160

Institutions

61

  1. The University of Osaka

    Osaka, Japan

    3 h-index

    6 publications

    124 citations

  2. Ajinomoto (Japan)

    Tokyo, Japan

    2 h-index

    8 publications

    284 citations

  3. Kyoto University

    Kyoto, Japan

    2 h-index

    4 publications

    53 citations

  4. Suzuki (Japan)

    Hamamatsu, Japan

    2 h-index

    7 publications

    223 citations

  5. Hokkaido University

    Sapporo, Japan

    2 h-index

    8 publications

    328 citations

  6. Nippon Soken (Japan)

    Nishio, Japan

    1 h-index

    1 publications

    352 citations

  7. Institute of Chemistry of Molecular Recognition

    Milan, Italy

    1 h-index

    3 publications

    66 citations

  8. Österreichisches Forschungsinstitut für Chemie und Technik

    Vienna, Austria

    1 h-index

    1 publications

    24 citations

1–8 of 61

Venues

  1. Journal of Molecular Biology

    JMB · 3 publications · 241 citations

    3

    h-index

  2. Proteins Structure Function and Bioinformatics

    2 publications · 108 citations

    2

    h-index

  3. PubMed

    Repository · 2 publications · 176 citations

    2

    h-index

  4. Biochemical and Biophysical Research Communications

    BBRC · 1 publications · 10 citations

    1

    h-index

  5. Oncogene

    1 publications · 17 citations

    1

    h-index

1–5