Gary Thomas

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen.

Sean S. Molloy, Patricia A. Bresnahan, S H Leppla et al. · Journal of Biological Chemistry · 1992 · 690 citations · Full text

Toxin Protective Antigen, Protein Secretion, Immunology +18

PACS‐2 controls endoplasmic reticulum–mitochondria communication and Bid‐mediated apoptosis

Thomas Simmen, Joseph E. Aslan, Anastassia D. Blagoveshchenskaya et al. · The EMBO Journal · 2005 · 569 citations · Full text

Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin.

Kurt R. Klimpel, Sean S. Molloy, Gary Thomas et al. · Proceedings of the National Academy of Sciences · 1992 · 458 citations · Full text

Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo.

Patricia A. Bresnahan, Richard Leduc, Laurel Thomas et al. · The Journal of Cell Biology · 1990 · 381 citations · Full text

Protein Secretion, Genetics, Immunology +23

PACS-1 Defines a Novel Gene Family of Cytosolic Sorting Proteins Required for trans-Golgi Network Localization

Lei Wan, Sean S. Molloy, Laurel Thomas et al. · Cell · 1998 · 378 citations · Full text

Signal Transduction, Novel Gene Family, Molecular Biology +10