Concepedia

Kurt R. Klimpel

KR

29

Publications

5.6K

Citations

27

H-Index

1987

Active since

Affiliations

National Institute of Dental and Craniofacial Research(Current)

National Institutes of Health

California State University, San Marcos

University of California San Diego

International Centre for Genetic Engineering and Biotechnology

Kurt R. Klimpel is an author at National Institute of Dental and Craniofacial Research specializing in medicine, pathogenesis, and microbiology.

Top concepts

Publications per year

1987–2003

29

Publications

29

Proteolytic Inactivation of MAP-Kinase-Kinase by Anthrax Lethal Factor

Nicholas S. Duesbery, Craig P. Webb, Stephen H. Leppla et al. · Science · 1998 · 1K citations

, , +19

Crystal structure of the anthrax toxin protective antigen

Carlo Petosa, R. John Collier, Kurt R. Klimpel et al. · Nature · 1997 · 754 citations

, , +4

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen.

Sean S. Molloy, Patricia A. Bresnahan, S H Leppla et al. · Journal of Biological Chemistry · 1992 · 690 citations · Full text

, , +18

Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin.

Kurt R. Klimpel, Sean S. Molloy, Gary Thomas et al. · Proceedings of the National Academy of Sciences · 1992 · 458 citations · Full text

Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity

Kurt R. Klimpel, Naveen Arora, Stephen H. Leppla · Molecular Microbiology · 1994 · 309 citations

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