Concepedia

Refolding Yield Optimization

Refolding Yield Optimization is a methodological framework in protein engineering that systematically enhances the efficiency of correctly folded protein recovery during refolding processes by minimizing aggregation and misfolding pathways.

53

Publications

2K

Citations

222

Authors

73

Institutions

Publications per year

2017–2026

3

Parents

Publications

53

Protein refolding at high concentration using size-exclusion chromatography

Boris Batas, Julian B. Chaudhuri · Biotechnology and Bioengineering · 1996 · 165 citations

, , +17

Urea gradient size-exclusion chromatography enhanced the yield of lysozyme refolding

Zhenyu Gu, Zhiguo Su, Jan‐Christer Janson · Journal of Chromatography A · 2001 · 127 citations · Full text

, , +13

A Universal Approach to Optimize the Folding and Stability of Prefusion-Closed HIV-1 Envelope Trimers

Lucy Rutten, Yen‐Ting Lai, Sven Blokland et al. · Cell Reports · 2018 · 116 citations · Full text

, , +17

Systematic Optimization of Expression and Refolding of the Plasmodium falciparum Cysteine Protease Falcipain-2

Puran Singh Sijwali, Linda S. Brinen, Philip J. Rosenthal · Protein Expression and Purification · 2001 · 102 citations

, , +14

High Pressure Refolding of Recombinant Human Growth Hormone from Insoluble Aggregates

Richard J. St. John, John F. Carpenter, Claude Balny et al. · Journal of Biological Chemistry · 2001 · 94 citations · Full text

, , +14

1–5 of 53

Authors

222

  1. ZS
    Zhiguo Su

    Institute of Process Engineering, China

    3 publications · 230 citations

    3

    h-index

  2. BB
    Boris Batas

    University of Bath, United Kingdom

    3 publications · 185 citations

    3

    h-index

  3. JB
    Julian B. Chaudhuri

    University of Bath, United Kingdom

    3 publications · 185 citations

    3

    h-index

  4. AP
    Anton P. J. Middelberg

    The University of Queensland, Australia

    3 publications · 86 citations

    3

    h-index

  5. BS
    Builder Se

    Atotech (United States), United States

    2 publications · 26 citations

    2

    h-index

1–5 of 222

Institutions

73

  1. University of Cambridge

    Cambridge, United Kingdom

    3 h-index

    7 publications

    186 citations

  2. University of Bath

    Bath, United Kingdom

    3 h-index

    7 publications

    380 citations

  3. Institute of Process Engineering

    Beijing, China

    3 h-index

    12 publications

    627 citations

  4. BOKU University

    Vienna, Austria

    2 h-index

    4 publications

    60 citations

  5. Indian Institute of Technology Delhi

    New Delhi, India

    2 h-index

    3 publications

    147 citations

  6. Inha University

    Incheon, South Korea

    2 h-index

    6 publications

    222 citations

  7. University College London

    London, United Kingdom

    2 h-index

    7 publications

    115 citations

  8. University of Colorado Boulder

    Boulder, United States

    2 h-index

    4 publications

    260 citations

1–8 of 73

Venues

  1. Biotechnology Progress

    8 publications · 239 citations

    8

    h-index

  2. Protein Expression and Purification

    6 publications · 214 citations

    6

    h-index

  3. Biotechnology and Bioengineering

    5 publications · 353 citations

    5

    h-index

  4. Journal of Chromatography A

    3 publications · 224 citations

    3

    h-index

  5. Process Biochemistry

    3 publications · 78 citations

    3

    h-index

1–5