Linda S. Brinen

Structural genomics of the <i>Thermotoga maritima</i> proteome implemented in a high-throughput structure determination pipeline

Scott A. Lesley, Peter Kühn, Adam Godzik et al. · Proceedings of the National Academy of Sciences · 2002 · 377 citations · Full text

Life Sciences, Biochemistry, Bioinformatics +14

Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design

Iain D. Kerr, Ji Hae Lee, Christopher J. Farady et al. · Journal of Biological Chemistry · 2009 · 297 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +15

Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense

Conor R. Caffrey, Elizabeth Hansell, Kimberley D. Lucas et al. · Molecular and Biochemical Parasitology · 2001 · 179 citations

Life Sciences, Microbiology, Molecular Biology +15

Structures of Falcipain-2 and Falcipain-3 Bound to Small Molecule Inhibitors: Implications for Substrate Specificity

Iain D. Kerr, Ji Hae Lee, Kailash C. Pandey et al. · Journal of Medicinal Chemistry · 2009 · 170 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

A pentahalogenated monoterpene from the red alga Portieria hornemannii produces a novel cytotoxicity profile against a diverse panel of human tumor cell lines

Richard W. Fuller, John H. Cardellina, Yōkō Kato et al. · Journal of Medicinal Chemistry · 1992 · 168 citations

Medicine, Oncology, Pharmacology +10