Concepedia

Christopher J. Farady

CJ

Statistics

Publications

25

Citations

3K

H-Index

19

Active since

2007

Affiliations

Novartis (Switzerland)(Current)

Novartis Institutes for BioMedical Research

University of California, San Francisco

University of Basel

Novartis (United States)

Christopher J. Farady is an author at Novartis (Switzerland) specializing in life sciences, inflammation, and innate immunity.

ORCID

Publications per year

2007–2025

25

Publications

25

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

Lorenzo Sborgi, Sebastian Rühl, Estefania Mulvihill et al. · The EMBO Journal · 2016 · 1.2K citations · Full text

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Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP3 inflammasome assembly

Kaiwen Chen, Benjamin Demarco, Rosalie Heilig et al. · The EMBO Journal · 2019 · 385 citations · Full text

, , +14

Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design

Iain D. Kerr, Ji Hae Lee, Christopher J. Farady et al. · Journal of Biological Chemistry · 2009 · 297 citations · Full text

, , +15

ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157

Dominik Feuerbach, Patrick Schindler, Carmen Barske et al. · Neuroscience Letters · 2017 · 186 citations

, , +4

Crystal Structure of NLRP3 NACHT Domain With an Inhibitor Defines Mechanism of Inflammasome Inhibition

Carien Dekker, Henri Mattes, Michael Wright et al. · Journal of Molecular Biology · 2021 · 160 citations

, , +16

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