Michael Wright

Cytotoxicity of polycations: Relationship of molecular weight and the hydrolytic theory of the mechanism of toxicity

Bryn D. Monnery, Michael Wright, Rachel Cavill et al. · International Journal of Pharmaceutics · 2017 · 220 citations · Full text

Hydrolytic Theory, Biochemistry, Medicine +6

GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo

M. Hauge, M. A. Vestmar, Anna Sofie Husted et al. · Molecular Metabolism · 2014 · 206 citations · Full text

Crystal Structure of NLRP3 NACHT Domain With an Inhibitor Defines Mechanism of Inflammasome Inhibition

Carien Dekker, Henri Mattes, Michael Wright et al. · Journal of Molecular Biology · 2021 · 149 citations

Crystal Structure, Anti-inflammatory, Signal Transduction +9

Synthesis of the potent influenza neuraminidase inhibitor 4-guanidino Neu5Ac2en. X-Ray molecular structure of 5-acetamido-4-amino-2,6-anhydro-3,4,5-trideoxy-D-erythro-L-gluco-nononic acid

Malcolm Chandler, Mark J. Bamford, Richard Conroy et al. · Journal of the Chemical Society Perkin Transactions 1 · 1995 · 89 citations

Organic Chemistry, Antiviral Drug, Chemical Biology +17

Discovery of a Novel Glucagon Receptor Antagonist<i>N</i>-[(4-{(1<i>S</i>)-1-[3-(3, 5-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1<i>H</i>-pyrazol-1-yl]ethyl}phenyl)carbonyl]-β-alanine (MK-0893) for the Treatment of Type II Diabetes

Yusheng Xiong, Jian Guo, Mari R. Candelore et al. · Journal of Medicinal Chemistry · 2012 · 86 citations · Full text