Paul A. Dalby

Two strategies to engineer flexible loops for improved enzyme thermostability

Haoran Yu, Yihan Yan, Cheng Zhang et al. · Scientific Reports · 2017 · 193 citations · Full text

One‐pot synthesis of amino‐alcohols using a de‐novo transketolase and β‐alanine: Pyruvate transaminase pathway in <i>Escherichia coli</i>

Christine Ursula Ingram, Martin Bommer, Mark E. B. Smith et al. · Biotechnology and Bioengineering · 2006 · 142 citations

Coupled molecular dynamics mediate long- and short-range epistasis between mutations that affect stability and aggregation kinetics

Haoran Yu, Paul A. Dalby · Proceedings of the National Academy of Sciences · 2018 · 124 citations · Full text

Optimising enzyme function by directed evolution

Paul A. Dalby · Current Opinion in Structural Biology · 2003 · 116 citations

Enzyme Function, Evolution Strategy, Engineering +7

Exploiting correlated molecular-dynamics networks to counteract enzyme activity–stability trade-off

Haoran Yu, Paul A. Dalby · Proceedings of the National Academy of Sciences · 2018 · 114 citations · Full text