Concepedia

Proteostasis

Proteostasis is a biological regulatory framework that maintains the proper folding, localization, and degradation of proteins within a cell to ensure proteome integrity.

857

Publications

49K

Citations

6.2K

Authors

1.5K

Institutions

Publications per year

2017–2026

603

Variants

Protein Homeostasis

Parents

Publications

857

FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging

Fabio Demontis, Norbert Perrimon · Cell · 2010 · 679 citations · Full text

, , +15

Collapse of proteostasis represents an early molecular event in <i>Caenorhabditis elegans</i> aging

Anat Ben‐Zvi, Elizabeth A. Miller, Richard I. Morimoto · Proceedings of the National Academy of Sciences · 2009 · 670 citations · Full text

, , +17

XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity

Rebecca C. Taylor, Andrew Dillin · Cell · 2013 · 617 citations · Full text

, , +14

Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments

Matthew D. Shoulders, Lisa M. Ryno, Joseph C. Genereux et al. · Cell Reports · 2013 · 583 citations · Full text

, , +15

Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1

Adam D. Cotton, Duy Nguyen, Josef A. Gramespacher et al. · Journal of the American Chemical Society · 2021 · 507 citations · Full text

, , +17

1–5 of 857

Authors

6.2K

  1. JW
    Jeffery W. Kelly

    Scripps Research Institute, United States

    19 publications · 1.8K citations

    17

    h-index

  2. RL
    R. Luke Wiseman

    Scripps Research Institute, United States

    17 publications · 2K citations

    16

    h-index

  3. RI
    Richard I. Morimoto

    Northwestern University, United States

    17 publications · 2.1K citations

    15

    h-index

  4. LP
    Lars Plate

    Vanderbilt University, United States

    12 publications · 1.1K citations

    12

    h-index

  5. MD
    Matthew D. Shoulders

    Massachusetts Institute of Technology, United States

    11 publications · 961 citations

    11

    h-index

1–5 of 6.2K

Institutions

1.5K

  1. Scripps Research Institute

    San Diego, United States

    30 h-index

    195 publications

    21.4K citations

  2. Harvard University

    Cambridge, United States

    28 h-index

    141 publications

    11.8K citations

  3. University of California, San Francisco

    San Francisco, United States

    20 h-index

    133 publications

    8.5K citations

  4. Northwestern University

    Evanston, United States

    19 h-index

    89 publications

    9.9K citations

  5. University of California San Diego

    San Diego, United States

    19 h-index

    98 publications

    6.4K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    18 h-index

    72 publications

    3.4K citations

  7. Inserm

    Paris, France

    18 h-index

    73 publications

    4.3K citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    18 h-index

    50 publications

    4.9K citations

1–8 of 1.5K

Venues

  1. Cell Reports

    42 publications · 3.3K citations

    31

    h-index

  2. Nature Communications

    38 publications · 2.7K citations

    28

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 31 publications · 3.5K citations

    28

    h-index

  4. eLife

    37 publications · 2.7K citations

    27

    h-index

  5. Journal of Biological Chemistry

    JBC · 32 publications · 1.7K citations

    24

    h-index

1–5