Josef A. Gramespacher

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Publications

Citations

1.1K

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Active since

2017

Affiliations

University of California, San Francisco(Current)

Princeton University

Chan Zuckerberg Initiative (United States)

Josef A. Gramespacher is an author at University of California, San Francisco specializing in molecular biology, protein engineering, and life sciences.

ORCID

Publications per year

2017–2022

Publications

Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1

Adam D. Cotton, Duy Nguyen, Josef A. Gramespacher et al. · Journal of the American Chemical Society · 2021 · 507 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Modular cytokine receptor-targeting chimeras for targeted degradation of cell surface and extracellular proteins

Katarina Pance, Josef A. Gramespacher, James R. Byrnes et al. · Nature Biotechnology · 2022 · 250 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Roadmap for Optimizing and Broadening Antibody-Based PROTACs for Degradation of Cell Surface Proteins

Josef A. Gramespacher, Adam D. Cotton, Paul W. W. Burroughs et al. · ACS Chemical Biology · 2022 · 94 citations

Life Sciences, Biochemistry, Molecular Biology +17

Intein Zymogens: Conditional Assembly and Splicing of Split Inteins via Targeted Proteolysis

Josef A. Gramespacher, Adam J. Stevens, Duy Nguyen et al. · Journal of the American Chemical Society · 2017 · 59 citations · Full text

Engineering, Chemical Biology, Molecular Biology +10

Trimeric SARS-CoV-2 Spike interacts with dimeric ACE2 with limited intra-Spike avidity

Irene Lui, Xin Zhou, Shion A. Lim et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 50 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +14

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