R. Luke Wiseman

Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade

Christine Bulawa, Stephen Connelly, Michael J. DeVit et al. · Proceedings of the National Academy of Sciences · 2012 · 728 citations · Full text

Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments

Matthew D. Shoulders, Lisa M. Ryno, Joseph C. Genereux et al. · Cell Reports · 2013 · 572 citations · Full text

Molecular Regulation, Molecular Biology, Transcriptional Regulation +19

Prevention of Transthyretin Amyloid Disease by Changing Protein Misfolding Energetics

Per Hammarström, R. Luke Wiseman, Evan T. Powers et al. · Science · 2003 · 520 citations

Protein Chemistry, Amyloid State, Alzheimer's Disease +15

The Biological and Chemical Basis for Tissue-Selective Amyloid Disease

Yoshiki Sekijima, R. Luke Wiseman, Jeanne Matteson et al. · Cell · 2005 · 486 citations · Full text

Alzheimer's Disease, Tissue-selective Amyloid Disease, Biochemistry +2

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics

Amado Carreras‐Sureda, Fabián Jaña, Hery Urra et al. · Nature Cell Biology · 2019 · 263 citations · Full text

Signal Transduction, Molecular Physiology, Mitochondrial Function +12