R. Luke Wiseman

Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade

Christine Bulawa, Stephen Connelly, Michael J. DeVit et al. · Proceedings of the National Academy of Sciences · 2012 · 742 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +15

Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments

Matthew D. Shoulders, Lisa M. Ryno, Joseph C. Genereux et al. · Cell Reports · 2013 · 583 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Prevention of Transthyretin Amyloid Disease by Changing Protein Misfolding Energetics

Per Hammarström, R. Luke Wiseman, Evan T. Powers et al. · Science · 2003 · 522 citations

Life Sciences, Biochemistry, Molecular Biology +17

The Biological and Chemical Basis for Tissue-Selective Amyloid Disease

Yoshiki Sekijima, R. Luke Wiseman, Jeanne Matteson et al. · Cell · 2005 · 494 citations · Full text

Life Sciences, Biochemistry, Neuroscience +14

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics

Amado Carreras‐Sureda, Fabián Jaña, Hery Urra et al. · Nature Cell Biology · 2019 · 277 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16