Concepedia

Personalized Gene Correction

Personalized Gene Correction is a precision genome editing strategy that specifically corrects disease-causing alleles in an individual's genome using allele-specific targeting, thereby preserving the endogenous regulatory context and genetic background unique to the patient.

12

Publications

1.6K

Citations

113

Authors

45

Institutions

Publications per year

2017–2026

6

Parents

Publications

12

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

Kosuke Yusa, S. Tamir Rashid, Hélène Strick‐Marchand et al. · Nature · 2011 · 640 citations · Full text

, , +13

Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs

Guang‐Hui Liu, Keiichiro Suzuki, Jing Qu et al. · Cell stem cell · 2011 · 217 citations · Full text

, , +10

Targeted exon skipping as a potential gene correction therapy for Duchenne muscular dystrophy

Annemieke Aartsma‐Rus, Mattie Bremmer-Bout, Anneke A. M. Janson et al. · Neuromuscular Disorders · 2002 · 175 citations

, , +13

Targeted Gene Correction Minimally Impacts Whole-Genome Mutational Load in Human-Disease-Specific Induced Pluripotent Stem Cell Clones

Keiichiro Suzuki, Chang Yu, Jing Qu et al. · Cell stem cell · 2014 · 174 citations · Full text

, , +14

Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts

Sara E. Howden, John P. Maufort, Bret Duffin et al. · Stem Cell Reports · 2015 · 103 citations · Full text

, , +16

1–5 of 12

Authors

113

  1. KS
    Keiichiro Suzuki

    The University of Osaka, Japan

    2 publications · 391 citations

    2

    h-index

  2. GL
    Guang‐Hui Liu

    Chinese Academy of Sciences, China

    2 publications · 391 citations

    2

    h-index

  3. AG
    April Goebl

    Salk Institute for Biological Studies, United States

    2 publications · 391 citations

    2

    h-index

  4. JC
    Juan Carlos Izpisúa Belmonte

    Salk Institute for Biological Studies, United States

    2 publications · 391 citations

    2

    h-index

  5. JQ
    Jing Qu

    Chinese Academy of Sciences, China

    2 publications · 391 citations

    2

    h-index

1–5 of 113

Institutions

45

  1. Salk Institute for Biological Studies

    La Jolla, United States

    2 h-index

    24 publications

    4.7K citations

  2. Glocal University

    Sahāranpur, India

    1 h-index

    2 publications

    44 citations

  3. Inserm

    Paris, France

    1 h-index

    3 publications

    1.9K citations

  4. Chinese Institute for Brain Research

    Beijing, China

    1 h-index

    1 publications

    174 citations

  5. Monash University

    Melbourne, Australia

    1 h-index

    2 publications

    206 citations

  6. Cambridge University Hospitals NHS Foundation Trust

    Cambridge, United Kingdom

    1 h-index

    1 publications

    640 citations

  7. Institut Pasteur

    Paris, France

    1 h-index

    3 publications

    1.9K citations

  8. Wellcome Sanger Institute

    Cambridge, United Kingdom

    1 h-index

    3 publications

    1.9K citations

1–8 of 45

Venues

  1. Cell stem cell

    2 publications · 391 citations

    2

    h-index

  2. Molecular Therapy — Nucleic Acids

    2 publications · 67 citations

    2

    h-index

  3. Journal of Community Genetics

    1 publications · 25 citations

    1

    h-index

  4. Blood

    1 publications · 21 citations

    1

    h-index

  5. Neuromuscular Disorders

    1 publications · 175 citations

    1

    h-index

1–5