In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration

Keiichiro Suzuki, Yuji Tsunekawa, Reyna Hernández‐Benítez, +32

Nature

In Vivo Gene TherapyGeneticsMolecular BiologyGenetic EngineeringGene Editing +4

Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2

Xi Xu, Chengcheng Yu, Jing Qu, +15

European Journal of Nuclear Medicine and Molecular Imaging

NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK

Guang‐Hui Liu, Jing Qu, Xun Shen

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

InflammationTranscriptional RegulationSignal TransductionSignaling PathwayMolecular Pathway +6

Single-Cell Transcriptomic Atlas of Primate Ovarian Aging

Si Wang, Yuxuan Zheng, Jingyi Li, +18

Cell

LongevityMedicineCellular SenescenceOmicsSingle-cell Transcriptomic Atlas +4

Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome

Guang‐Hui Liu, Basam Z. Barkho, Sergio Ruiz, +14

Nature

LongevityPediatrics

A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging

Weiqi Zhang, Jingyi Li, Keiichiro Suzuki, +31

Science

Repression of the Antioxidant NRF2 Pathway in Premature Aging

Nard Kubben, Weiqi Zhang, Lixia Wang, +5

Cell

AgingLongevityPhysiologyPremature AgingReactive Oxygen Specie +5

Artificial MicroRNA-Mediated Virus Resistance in Plants

Jing Qu, Jian Ye, Rongxiang Fang

Journal of Virology

A Single-Cell Transcriptomic Atlas of Human Skin Aging

Zhiran Zou, Xiao Long, Qian Zhao, +15

Developmental Cell

Skin DevelopmentMedicineHuman Skin AgingSingle-cell GenomicsCellular Senescence +4

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

Guang‐Hui Liu, Jing Qu, Keiichiro Suzuki, +20

Nature

NeuroregenerationDevelopmental BiologyProgressive DegenerationMedicineAdult Stem Cell +6