Kosuke Yusa

Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens

Fiona M. Behan, Francesco Iorio, Gabriele Picco et al. · Nature · 2019 · 1.3K citations · Full text

Crispr–cas9 Screens, Gene Editing, Genome Editing +4

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

Hiroko Koike-Yusa, Yilong Li, E‐Pien Tan et al. · Nature Biotechnology · 2013 · 1.1K citations

Medicine, Genetics, Genetic Engineering +6

A hyperactive <i>piggyBac</i> transposase for mammalian applications

Kosuke Yusa, Liqin Zhou, Meng Amy Li et al. · Proceedings of the National Academy of Sciences · 2011 · 797 citations · Full text

Signal Transduction, Developmental Biology, Dna Transposons +13

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia

Konstantinos Tzelepis, Hiroko Koike-Yusa, Étienne De Braekeleer et al. · Cell Reports · 2016 · 784 citations · Full text

Gene Deletion Data, Genetics, Acute Myeloid Leukemia +9

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

Kosuke Yusa, S. Tamir Rashid, Hélène Strick‐Marchand et al. · Nature · 2011 · 638 citations · Full text

α1-Antitrypsin Deficiency, Induced Pluripotent Stem Cell, Medicine +7