Konstantinos Tzelepis

Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia

Eliza Yankova, Wesley Blackaby, Mark R. Albertella et al. · Nature · 2021 · 1.3K citations · Full text

Medicine, Oncology, Pharmacology +13

Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control

Isaia Barbieri, Konstantinos Tzelepis, Luca Pandolfini et al. · Nature · 2017 · 1.1K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +13

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia

Konstantinos Tzelepis, Hiroko Koike-Yusa, Étienne De Braekeleer et al. · Cell Reports · 2016 · 834 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

RNA modifications detection by comparative Nanopore direct RNA sequencing

Adrien Léger, Paulo Amaral, Luca Pandolfini et al. · Nature Communications · 2021 · 424 citations · Full text

Life Sciences, Molecular Biology, Gene Expression +9

METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation

Esteban A. Orellana, Qi Liu, Eliza Yankova et al. · Molecular Cell · 2021 · 362 citations · Full text

Medicine, Cancer Biology, Molecular Biology +7