Concepedia

Oncogene Addiction

Oncogene Addiction is a phenomenon in cancer biology wherein a cancer cell becomes dependent on the continued activity of a specific oncogene for its survival and proliferation, despite the presence of other genetic alterations.

215

Publications

23.9K

Citations

1.9K

Authors

540

Institutions

Publications per year

2017–2026

89

Parents

Children

Publications

215

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

David R. Wise, Ralph J. DeBerardinis, Anthony Mancuso et al. · Proceedings of the National Academy of Sciences · 2008 · 2K citations · Full text

, , +17

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

Ji Luo, Nicole L. Solimini, Stephen J. Elledge · Cell · 2009 · 1.8K citations · Full text

, , +14

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma

Pedro P. Medina, Mona J. Nolde, Frank J. Slack · Nature · 2010 · 968 citations

, , +12

A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival

Anurag Singh, Patricia Greninger, Daniel R. Rhodes et al. · Cancer Cell · 2009 · 864 citations · Full text

, , +14

Oncogene-addicted metastatic non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

Lizza Hendriks, Keith M. Kerr, Jessica Menis et al. · Annals of Oncology · 2023 · 790 citations · Full text

, , +14

1–5 of 215

Authors

1.9K

  1. DW
    Dean W. Felsher

    Stanford University, United States

    9 publications · 398 citations

    9

    h-index

  2. SG
    Silvia Giordano

    Candiolo Cancer Institute, Italy

    6 publications · 415 citations

    6

    h-index

  3. DP
    David Planchard

    Institut Gustave Roussy, France

    5 publications · 1.6K citations

    5

    h-index

  4. PM
    Paolo M. Comoglio

    University of Turin, Italy

    5 publications · 375 citations

    5

    h-index

  5. AP
    Antonio Passaro

    European Institute of Oncology, Italy

    4 publications · 1.4K citations

    4

    h-index

1–5 of 1.9K

Institutions

540

  1. Harvard University

    Cambridge, United States

    20 h-index

    130 publications

    27.5K citations

  2. Dana-Farber Cancer Institute

    Boston, United States

    16 h-index

    110 publications

    19.8K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    13 h-index

    21 publications

    7.9K citations

  4. Istituti di Ricovero e Cura a Carattere Scientifico

    Rome, Italy

    12 h-index

    56 publications

    3.5K citations

  5. Candiolo Cancer Institute

    Candiolo, Italy

    11 h-index

    71 publications

    4.3K citations

  6. Center for Cancer Research

    Bethesda, United States

    10 h-index

    32 publications

    7.7K citations

  7. University of Turin

    Turin, Italy

    10 h-index

    50 publications

    3.5K citations

  8. Stanford University

    Stanford, United States

    10 h-index

    54 publications

    1.8K citations

1–8 of 540

Venues

  1. Cancer Cell

    13 publications · 3.5K citations

    13

    h-index

  2. Oncotarget

    12 publications · 752 citations

    12

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 10 publications · 2.7K citations

    10

    h-index

  4. Oncogene

    10 publications · 356 citations

    10

    h-index

  5. Cancer Research

    8 publications · 517 citations

    8

    h-index

1–5