Concepedia

Myc Dependency

MYC Dependency is a biological phenomenon in cancer cells wherein sustained oncogenic proliferation and survival are critically reliant on the continued expression and activity of the MYC oncogene, despite the presence of other genetic alterations.

120

Publications

10.4K

Citations

947

Authors

295

Institutions

Publications per year

2017–2026

32

Variants

Myc Addiction

Parents

Publications

120

PVT1 dependence in cancer with MYC copy-number increase

Yuen‐Yi Tseng, Branden S. Moriarity, Wuming Gong et al. · Nature · 2014 · 738 citations

, , +14

HIF‐1α induces cell cycle arrest by functionally counteracting Myc

Minori Koshiji, Yukio Kageyama, Erin A. Pete et al. · The EMBO Journal · 2004 · 647 citations · Full text

, , +14

The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration

Melanie Clements, Elizabeth H. Byrne, Luis F. Camarillo Guerrero et al. · Neuron · 2017 · 338 citations · Full text

, , +16

Regulation of <i>cyclin D2</i> gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the <i>cyclin D2</i> promoter

Caroline Bouchard, Oliver Dittrich, Astrid Kiermaier et al. · Genes & Development · 2001 · 335 citations · Full text

, , +17

Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src

Maria Vittoria Barone, Sara A. Courtneidge · Nature · 1995 · 310 citations

, , +14

1–5 of 120

Authors

947

  1. GI
    Gérard I. Evan

    University of California, San Francisco, United States

    5 publications · 421 citations

    5

    h-index

  2. ME
    Martin Eilers

    University of Würzburg, Germany

    4 publications · 787 citations

    4

    h-index

  3. BA
    Bruno Amati

    European Institute of Oncology, Italy

    3 publications · 225 citations

    3

    h-index

  4. AT
    Andreas Trumpp

    Heidelberg University, Germany

    3 publications · 452 citations

    3

    h-index

  5. AV
    Alessandro Verrecchia

    European Institute of Oncology, Italy

    3 publications · 225 citations

    3

    h-index

1–5 of 947

Institutions

295

  1. Dana-Farber Cancer Institute

    Boston, United States

    6 h-index

    61 publications

    8.1K citations

  2. Harvard University

    Cambridge, United States

    5 h-index

    53 publications

    5.8K citations

  3. Heidelberg University

    Heidelberg, Germany

    5 h-index

    26 publications

    2.6K citations

  4. Italian Institute of Technology

    Genoa, Italy

    4 h-index

    16 publications

    1.1K citations

  5. European Institute of Oncology

    Milan, Italy

    4 h-index

    23 publications

    2.4K citations

  6. University of Pennsylvania

    Philadelphia, United States

    4 h-index

    15 publications

    4K citations

  7. German Cancer Research Center

    Heidelberg, Germany

    4 h-index

    24 publications

    2K citations

  8. Karolinska Institutet

    Stockholm, Sweden

    4 h-index

    15 publications

    475 citations

1–8 of 295

Venues

  1. Oncogene

    15 publications · 989 citations

    15

    h-index

  2. Nature

    6 publications · 2K citations

    6

    h-index

  3. PubMed

    Repository · 6 publications · 136 citations

    6

    h-index

  4. Blood

    5 publications · 255 citations

    5

    h-index

  5. Nature Communications

    4 publications · 169 citations

    4

    h-index

1–5