Yuen‐Yi Tseng

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

Yilong Zou, Michael J. Palte, Amy Deik et al. · Nature Communications · 2019 · 829 citations · Full text

Patient-derived xenografts undergo mouse-specific tumor evolution

Uri Ben‐David, Gavin Ha, Yuen‐Yi Tseng et al. · Nature Genetics · 2017 · 703 citations · Full text

Lineage Plasticity, Xenotransplantation, Tumor Heterogeneity +4

WRN helicase is a synthetic lethal target in microsatellite unstable cancers

Edmond M. Chan, Tsukasa Shibue, James M. McFarland et al. · Nature · 2019 · 448 citations · Full text

Microsatellite Unstable Cancers, Oncogenic Agent, Medicine +8

Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood

Julia Joung, J Engreitz, Silvana Konermann et al. · Nature · 2017 · 432 citations

Chromatin, Genome-scale Activation Screen, Lncrna Locus +9

Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development

Krinio Giannikou, Izabela A. Malinowska, Trevor J. Pugh et al. · PLoS Genetics · 2016 · 125 citations · Full text

Urology, Somatic Variant, Renal Angiomyolipoma Development +14