Concepedia

Oncogenic Driver Mutations

Oncogenic Driver Mutations is a genetic alteration in a gene that confers a selective growth advantage to a cancer cell by directly promoting tumorigenesis, distinguishing it from passenger mutations that lack functional consequences in cancer progression.

2.3K

Publications

206.3K

Citations

23.1K

Authors

3.4K

Institutions

Publications per year

2017–2026

1.4K

Variants

Oncogenic Driver Mutation

Parents

Publications

2.3K

The Immune Landscape of Cancer

Vésteinn Thórsson, David L. Gibbs, Scott D. Brown et al. · Immunity · 2018 · 6.2K citations · Full text

, , +17

Mutational landscape and significance across 12 major cancer types

Cyriac Kandoth, Michael D. McLellan, Fabio Vandin et al. · Nature · 2013 · 4.5K citations · Full text

, , +17

Integrated Genomic Characterization of Papillary Thyroid Carcinoma

Nishant Agrawal, Rehan Akbani, Bülent Arman Aksoy et al. · Cell · 2014 · 3.1K citations · Full text

, , +17

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu et al. · Nature · 2012 · 2.7K citations

, , +16

A Landscape of Driver Mutations in Melanoma

Eran Hodis, Ian R. Watson, Gregory V. Kryukov et al. · Cell · 2012 · 2.6K citations · Full text

, , +12

1–5 of 2.3K

Authors

23.1K

  1. GG
    Gad Getz

    Broad Institute, United States

    35 publications · 21.5K citations

    28

    h-index

  2. PA
    P. Andrew Futreal

    The University of Texas MD Anderson Cancer Center, United States

    26 publications · 7.2K citations

    25

    h-index

  3. GB
    Gordon B. Mills

    The University of Texas MD Anderson Cancer Center, United States

    22 publications · 14.7K citations

    21

    h-index

  4. NS
    Nikolaus Schultz

    Memorial Sloan Kettering Cancer Center, United States

    20 publications · 15.2K citations

    20

    h-index

  5. DC
    David C. Wedge

    Wellcome Sanger Institute, United Kingdom

    20 publications · 8.9K citations

    20

    h-index

1–5 of 23.1K

Institutions

3.4K

  1. Dana-Farber Cancer Institute

    Boston, United States

    74 h-index

    836 publications

    247.4K citations

  2. Harvard University

    Cambridge, United States

    71 h-index

    843 publications

    225.3K citations

  3. The University of Texas MD Anderson Cancer Center

    Houston, United States

    65 h-index

    1.1K publications

    475K citations

  4. Memorial Sloan Kettering Cancer Center

    New York, United States

    63 h-index

    1K publications

    218.9K citations

  5. Johns Hopkins University

    Baltimore, United States

    51 h-index

    498 publications

    97K citations

  6. Broad Institute

    Cambridge, United States

    51 h-index

    1K publications

    428.5K citations

  7. Brigham and Women's Hospital

    Boston, United States

    51 h-index

    257 publications

    46.5K citations

  8. Massachusetts General Hospital

    Boston, United States

    50 h-index

    465 publications

    100.9K citations

1–8 of 3.4K

Venues

  1. Nature Communications

    98 publications · 12.5K citations

    60

    h-index

  2. Cancer Research

    91 publications · 6.6K citations

    42

    h-index

  3. Oncotarget

    81 publications · 3.8K citations

    39

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 51 publications · 6.4K citations

    39

    h-index

  5. Clinical Cancer Research

    59 publications · 5.8K citations

    38

    h-index

1–5