Concepedia

Metabolic Tolerance

Metabolic Tolerance is a pharmacological phenomenon within the broader category of drug tolerance, characterized by an accelerated rate of drug metabolism due to enhanced activity of metabolic enzymes, typically resulting in reduced drug efficacy over time.

174

Publications

9.7K

Citations

744

Authors

259

Institutions

Publications per year

2017–2026

11

Parents

Publications

174

LIQUID DIET TECHNIQUE OF ETHANOL ADMINISTRATION: 1989 UPDATE

C S Lieber, Leonore M. DeCarli · Alcohol and Alcoholism · 1989 · 427 citations

, , +17

Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet

Xiang Gao, Xiaofang Liu, Jie Xu et al. · Journal of Bioscience and Bioengineering · 2014 · 349 citations

, , +13

Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance

Kirthana Ganeshan, Joni Nikkanen, Kevin Man et al. · Cell · 2019 · 287 citations · Full text

, , +14

Metabolic Adaptation Establishes Disease Tolerance to Sepsis

Sebastian Weis, Ana Rita Carlos, Maria Raquel Moita et al. · Cell · 2017 · 282 citations · Full text

, , +17

Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance

Karsten Sydow, Andreas Daiber, Matthias Oelze et al. · Journal of Clinical Investigation · 2004 · 273 citations · Full text

, , +17

1–5 of 174

Authors

744

  1. PS
    Peter Spégel

    Lund University, Sweden

    3 publications · 107 citations

    3

    h-index

  2. RN
    Richard N. Bergman

    University of Southern California, United States

    3 publications · 540 citations

    3

    h-index

  3. AP
    Anders P. H. Danielsson

    Lund University, Sweden

    3 publications · 107 citations

    3

    h-index

  4. YI
    Yedy Israel

    University of Toronto, Canada

    3 publications · 99 citations

    3

    h-index

  5. JF
    Jean Fiet

    Hôpital Saint-Louis, France

    3 publications · 72 citations

    3

    h-index

1–5 of 744

Institutions

259

  1. Lund University

    Lund, Sweden

    6 h-index

    24 publications

    998 citations

  2. University of Toronto

    Toronto, Canada

    5 h-index

    18 publications

    900 citations

  3. Inserm

    Paris, France

    4 h-index

    16 publications

    2K citations

  4. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    4 h-index

    12 publications

    470 citations

  5. National Institutes of Health

    Bethesda, United States

    4 h-index

    6 publications

    365 citations

  6. United States Department of Veterans Affairs

    Washington, United States

    3 h-index

    3 publications

    460 citations

  7. Duke Medical Center

    Durham, United States

    3 h-index

    8 publications

    1.3K citations

  8. Icahn School of Medicine at Mount Sinai

    New York, United States

    3 h-index

    8 publications

    1K citations

1–8 of 259

Venues

  1. PubMed

    Repository · 18 publications · 395 citations

    12

    h-index

  2. Diabetes

    11 publications · 1.1K citations

    11

    h-index

  3. Metabolism

    8 publications · 342 citations

    8

    h-index

  4. Diabetes Research and Clinical Practice

    7 publications · 188 citations

    7

    h-index

  5. Alcoholism Clinical and Experimental Research

    ACER · 8 publications · 360 citations

    7

    h-index

1–5