Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

Laura K. Mackay, Martina Minnich, Natasja A. M. Kragten, +22

Science

HistocompatibilityTissue-resident Memory TLymphocyte DevelopmentT-regulatory CellImmunology +17

Transcription Factor IRF4 Promotes CD8+ T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection

Kevin Man, Sarah S. Gabriel, Yang Liao, +9

Immunity

T-regulatory CellImmunologyMemory-like T CellsAutoimmunityT Cell Immunity +5

CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles

Yew Ann Leong, Yaping Chen, Hong Sheng Ong, +34

Nature Immunology

Autoimmune DiseaseMedicinePathogenesisImmunologyImmunologic Mechanism +5

The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells

Kevin Man, Maria Miasari, Wei Shi, +9

Nature Immunology

Transcriptional RegulationTranscription FactorsSignal TransductionSignaling PathwayT Cells +12

Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance

Kirthana Ganeshan, Joni Nikkanen, Kevin Man, +7

Cell

Energy HomeostasisEnergy MetabolismSignal TransductionPhysiologyMetabolism +3

PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia

Helen M. McRae, Alexandra L. Garnham, Yifang Hu, +24

Blood

Two regulatory T cell populations in the visceral adipose tissue shape systemic metabolism

Santiago Valle Torres, Kevin Man, Tarek Elmzzahi, +23

Nature Immunology

ObesityMetabolic SyndromeBody CompositionMetabolic DisorderCell Signaling +12

Unlocking autofluorescence in the era of full spectrum analysis: Implications for immunophenotype discovery projects

Vanta Jameson, Tina Luke, Yuting Yan, +8

Cytometry Part A

Immunocytochemical TechniqueEngineeringImmunologyMolecular BiologyImmunophenotyping +22

Lymph-node-derived stem-like but not tumor-tissue-resident CD8+ T cells fuel anticancer immunity

Sharanya K M Wijesinghe, Lisa Rausch, Sarah S. Gabriel, +26

Nature Immunology

A thermogenic fat-epithelium cell axis regulates intestinal disease tolerance

Kevin Man, Christopher Bowman, Kristina N. Braverman, +9

Proceedings of the National Academy of Sciences