Concepedia

Lysosomal Trafficking

Lysosomal Trafficking is the intracellular membrane trafficking process that specifically governs the sorting, delivery, and recycling of lysosomal membrane and soluble proteins between the trans-Golgi network, endosomes, autophagosomes, and the plasma membrane to establish and maintain functional lysosomes and their degradative capacity.

4.3K

Publications

366K

Citations

17.3K

Authors

2.8K

Institutions

Publications per year

2017–2026

965

Parents

Children

Publications

4.3K

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

Joseph L. Goldstein, Y K Ho, Sandip K. Basu et al. · Proceedings of the National Academy of Sciences · 1979 · 2.5K citations · Full text

, , +17

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

Yasemin Sancak, Liron Bar‐Peled, Roberto Zoncu et al. · Cell · 2010 · 2.4K citations · Full text

, , +17

Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy

Ana María Cuervo, Leonidas Stefanis, Ross A. Fredenburg et al. · Science · 2004 · 2K citations

, , +17

Lysosomes in biology and pathology

Food and Cosmetics Toxicology · 1977 · 2K citations

, , +10

A lysosome‐to‐nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

Carmine Settembre, Roberto Zoncu, Diego L. Medina et al. · The EMBO Journal · 2012 · 1.9K citations · Full text

, , +12

1–5 of 4.3K

Authors

17.3K

  1. JS
    Juan S. Bonifacino

    National Institutes of Health, United States

    33 publications · 6.1K citations

    33

    h-index

  2. KV
    Kurt Von Figura

    University of Göttingen, Germany

    40 publications · 3.7K citations

    30

    h-index

  3. PS
    Paul Säftig

    Christian-Albrechts-Universität zu Kiel, Germany

    36 publications · 4K citations

    29

    h-index

  4. NW
    Norma W. Andrews

    Yale University, United States

    29 publications · 5.4K citations

    28

    h-index

  5. JK
    Judith Klumperman

    University Medical Center Utrecht, Netherlands

    28 publications · 4.8K citations

    26

    h-index

1–5 of 17.3K

Institutions

2.8K

  1. National Institutes of Health

    Bethesda, United States

    87 h-index

    700 publications

    112.2K citations

  2. Yale University

    New Haven, United States

    59 h-index

    275 publications

    57.1K citations

  3. Washington University in St. Louis

    St Louis, United States

    59 h-index

    305 publications

    53.1K citations

  4. Harvard University

    Cambridge, United States

    53 h-index

    252 publications

    36.8K citations

  5. Inserm

    Paris, France

    52 h-index

    435 publications

    30.5K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    48 h-index

    136 publications

    30.5K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    48 h-index

    387 publications

    27.3K citations

  8. University of Cambridge

    Cambridge, United Kingdom

    44 h-index

    249 publications

    32.4K citations

1–8 of 2.8K

Venues

  1. The Journal of Cell Biology

    JCB · 272 publications · 41.2K citations

    125

    h-index

  2. Journal of Biological Chemistry

    JBC · 354 publications · 34.7K citations

    107

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 127 publications · 21.3K citations

    77

    h-index

  4. Journal of Cell Science

    185 publications · 15.3K citations

    70

    h-index

  5. Molecular Biology of the Cell

    MBC · 132 publications · 14.5K citations

    68

    h-index

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