Concepedia

Isolation Membrane Dynamics

Isolation Membrane Dynamics is a theoretical construct in cell biology that describes the spatiotemporal regulation of membrane expansion, curvature, and closure during autophagosome formation, distinguishing it from static models of autophagosomal membrane assembly by emphasizing the dynamic coordination of lipid transfer, protein scaffolding, and organelle interactions.

9

Publications

971

Citations

56

Authors

22

Institutions

Publications per year

2017–2026

5

Parents

Publications

9

Golgi-resident Small GTPase Rab33B Interacts with Atg16L and Modulates Autophagosome Formation

Takashi Itoh, Naonobu Fujita, Eiko Kanno et al. · Molecular Biology of the Cell · 2008 · 258 citations · Full text

, , +11

The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation

Yan Zhao, Yong Chen, Guangyan Miao et al. · Molecular Cell · 2017 · 229 citations · Full text

, , +12

CapZ regulates autophagosomal membrane shaping by promoting actin assembly inside the isolation membrane

Na Mi, Shuai Wang, Mengran Chen et al. · Nature Cell Biology · 2015 · 150 citations

, , +13

Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons

Andrea KH Stavoe, Pallavi P. Gopal, Andrea Gubaš et al. · eLife · 2019 · 81 citations · Full text

, , +17

Dynamics and function of PtdIns(3) <i>P</i> in autophagy

Keisuke Obara, Yoshinori Ohsumi · Autophagy · 2008 · 71 citations · Full text

, , +12

1–5 of 9

Authors

56

  1. YO
    Yoshinori Ohsumi

    National Institute for Basic Biology, Japan

    2 publications · 100 citations

    2

    h-index

  2. DL
    Duncan L. McCollester

    National Heart Lung and Blood Institute, United States

    1 publications · 31 citations

    1

    h-index

  3. TT
    Takuma Tsuji

    Nagoya University, Japan

    1 publications · 71 citations

    1

    h-index

  4. WQ
    Wenyan Qu

    Chinese Academy of Sciences, China

    1 publications · 229 citations

    1

    h-index

  5. SC
    She Chen

    National Institute of Biological Sciences, Beijing, China

    1 publications · 229 citations

    1

    h-index

1–5 of 56

Institutions

22

  1. Juntendo University

    Tokyo, Japan

    2 h-index

    4 publications

    242 citations

  2. Innovative Research (United States)

    Minneapolis, United States

    1 h-index

    1 publications

    29 citations

  3. Tsinghua University

    Beijing, China

    1 h-index

    14 publications

    2.1K citations

  4. Institute of Biophysics

    Beijing, China

    1 h-index

    10 publications

    2.3K citations

  5. Chinese Academy of Sciences

    Beijing, China

    1 h-index

    10 publications

    2.3K citations

  6. The University of Tokyo

    Tokyo, Japan

    1 h-index

    3 publications

    153 citations

  7. Kyoto University

    Kyoto, Japan

    1 h-index

    1 publications

    29 citations

  8. The University of Osaka

    Osaka, Japan

    1 h-index

    2 publications

    516 citations

1–8 of 22

Venues

  1. PLoS ONE

    1 publications · 51 citations

    1

    h-index

  2. Nature Cell Biology

    NCB · 1 publications · 150 citations

    1

    h-index

  3. Nature Communications

    1 publications · 29 citations

    1

    h-index

  4. The Journal of Cell Biology

    JCB · 1 publications · 71 citations

    1

    h-index

  5. Autophagy

    1 publications · 71 citations

    1

    h-index

1–5