ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation

Guangyan Miao, Hongyu Zhao, Yan Li, +6

Developmental Cell

Virus StructureViral ReplicationMolecular BiologyVirologyAutolysosome Formation +5

The Vici Syndrome Protein EPG5 Is a Rab7 Effector that Determines the Fusion Specificity of Autophagosomes with Late Endosomes/Lysosomes

Wang Zheng, Guangyan Miao, Xue Xue, +8

Molecular Cell

Cell AutophagyMitophagyRab7 EffectorSignal TransductionAutoimmune Disease +10

The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation

Yan Zhao, Yong Chen, Guangyan Miao, +10

Molecular Cell

Cell AutophagyMitophagyEr-isolation Membrane ContactsSignal TransductionAutophagy +10

The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis

Yan Zhao, Nan Liu, Guangyan Miao, +3

Current Biology

Cell AutophagyMitophagySignal TransductionMedicineCell Interaction +7

The autophagy gene<i>Wdr45/Wipi4</i>regulates learning and memory function and axonal homeostasis

Yan Zhao, Le Sun, Guangyan Miao, +8

Autophagy

MitophagyAxonal HomeostasisWd40 Repeat-containing PtdinsDefective Axonal HomeostasisSynaptic Signaling +15

The ER-Localized Protein DFCP1 Modulates ER-Lipid Droplet Contact Formation

Dongfang Li, Yan Zhao, Di Li, +7

Cell Reports

Ld GrowthProteinlipid InteractionBiochemistryProtein FoldingNatural Sciences +11

PINK1, Keap1, and Rtnl1 regulate selective clearance of endoplasmic reticulum during development

Ruoxi Wang, Tina M. Fortier, Fei Chai, +6

Cell

Signal TransductionDevelopmental BiologyOrganelle DynamicNatural SciencesSecretory Pathway +8

The ER-Localized Transmembrane Protein TMEM39A/SUSR2 Regulates Autophagy by Controlling the Trafficking of the PtdIns(4)P Phosphatase SAC1

Guangyan Miao, Yujie Zhang, Di Chen, +1

Molecular Cell

P Phosphatase Sac1Cell AutophagySignal TransductionSignaling PathwayCell Signaling +9

Transmembrane Protein 208: A Novel ER-Localized Protein That Regulates Autophagy and ER Stress

Yuanbo Zhao, Jia Hu, Guangyan Miao, +6

PLoS ONE

Reductive StressCell AutophagyMitophagySignal TransductionNatural Sciences +13

Mice deficient in the Vici syndrome gene <i>Epg5</i> exhibit features of retinitis pigmentosa

Guangyan Miao, Yan Zhao, Hongyu Zhao, +4

Autophagy