Yong Chen

ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation

Guangyan Miao, Hongyu Zhao, Yan Li et al. · Developmental Cell · 2020 · 359 citations · Full text

Virus Structure, Viral Replication, Molecular Biology +7

Breast milk-derived exosomes promote intestinal epithelial cell growth

Alison Hock, Hiromu Miyake, Bo Li et al. · Journal of Pediatric Surgery · 2017 · 235 citations

Extracellular Vesicles, Mammary Gland, Extracellular Microvesicles +6

The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation

Yan Zhao, Yong Chen, Guangyan Miao et al. · Molecular Cell · 2017 · 223 citations · Full text

Cell Autophagy, Mitophagy, Er-isolation Membrane Contacts +12

Calcium transients on the ER surface trigger liquid-liquid phase separation of FIP200 to specify autophagosome initiation sites

Qiaoxia Zheng, Yong Chen, Di Chen et al. · Cell · 2022 · 190 citations

Bovine milk-derived exosomes enhance goblet cell activity and prevent the development of experimental necrotizing enterocolitis

Bo Li, Alison Hock, Richard Wu et al. · PLoS ONE · 2019 · 183 citations · Full text