Concepedia

Inhibitor Efficacy Testing

Inhibitor Efficacy Testing is a methodological framework in chemical biology that quantifies the functional capacity of a chemical inhibitor to modulate a target biomolecule's activity under controlled experimental conditions.

39

Publications

1.6K

Citations

259

Authors

95

Institutions

Publications per year

2017–2026

7

Parents

Publications

39

Firefly Luciferase in Chemical Biology: A Compendium of Inhibitors, Mechanistic Evaluation of Chemotypes, and Suggested Use As a Reporter

Natasha Thorne, Min Shen, Wendy Lea et al. · Chemistry & Biology · 2012 · 137 citations · Full text

, , +15

Carbon- versus sulphur-based zinc binding groups for carbonic anhydrase inhibitors?

Claudiu T. Supuran · Journal of Enzyme Inhibition and Medicinal Chemistry · 2018 · 122 citations · Full text

, , +16

New rapid test for evaluation of scale inhibitors

I. Drela, P. Falewicz, S. Kuczkowska · Water Research · 1998 · 111 citations

, , +10

Validation of Nijmegen–Bethesda assay modifications to allow inhibitor measurement during replacement therapy and facilitate inhibitor surveillance

Connie H. Miller, S. Jean Platt, A. Rice et al. · Journal of Thrombosis and Haemostasis · 2012 · 110 citations

, , +8

Solute Restriction Reveals an Essential Role for clag3-Associated Channels in Malaria Parasite Nutrient Acquisition

Ajay D. Pillai, Wang Nguitragool, Brian Lyko et al. · Molecular Pharmacology · 2012 · 89 citations · Full text

, , +17

1–5 of 39

Authors

259

  1. SL
    Stefan Laufer

    University of Tübingen, Germany

    2 publications · 40 citations

    2

    h-index

  2. GG
    Grazia Graziani

    University of Rome Tor Vergata, Italy

    1 publications · 12 citations

    1

    h-index

  3. BD
    Brian Dymock

    National University of Singapore, Singapore

    1 publications · 19 citations

    1

    h-index

  4. KL
    Kim L. Matthews

    CHDI Foundation, United States

    1 publications · 55 citations

    1

    h-index

  5. AO
    Akira Otaka

    Kyoto University, Japan

    1 publications · 16 citations

    1

    h-index

1–5 of 259

Institutions

95

  1. Philipps University of Marburg

    Marburg, Germany

    2 h-index

    3 publications

    97 citations

  2. United States Food and Drug Administration

    Silver Spring, United States

    2 h-index

    7 publications

    272 citations

  3. National Institutes of Health

    Bethesda, United States

    2 h-index

    10 publications

    938 citations

  4. Universidad de Navarra

    Pamplona, Spain

    1 h-index

    2 publications

    52 citations

  5. Xiamen University

    Xiamen, China

    1 h-index

    5 publications

    195 citations

  6. Chartered Institute of Management Accountants

    London, United Kingdom

    1 h-index

    1 publications

    26 citations

  7. University of Florence

    Florence, Italy

    1 h-index

    1 publications

    122 citations

  8. Hospital Universitario 12 De Octubre

    Madrid, Spain

    1 h-index

    2 publications

    52 citations

1–8 of 95

Venues

  1. PubMed

    Repository · 3 publications · 65 citations

    3

    h-index

  2. Journal of Medicinal Chemistry

    3 publications · 100 citations

    3

    h-index

  3. Analytical Biochemistry

    2 publications · 97 citations

    2

    h-index

  4. Journal of Computational Chemistry

    1 publications · 39 citations

    1

    h-index

  5. Chemistry & Biology

    1 publications · 137 citations

    1

    h-index

1–5