Kim L. Matthews

Noradrenergic changes, aggressive behavior, and cognition in patients with dementia

Kim L. Matthews, Christopher Chen, Margaret M. Esiri et al. · Biological Psychiatry · 2002 · 215 citations

Neuropsychology, Psychopathology, Psychiatry +13

Design, Synthesis, and Biological Evaluation of Potent and Selective Class IIa Histone Deacetylase (HDAC) Inhibitors as a Potential Therapy for Huntington’s Disease

Roland W. Bürli, Christopher A. Luckhurst, Omar Aziz et al. · Journal of Medicinal Chemistry · 2013 · 147 citations · Full text

Aldo-keto Reductase, Molecular Biology, Chemical Biology +19

GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility

Gareth J. Sanger, Susan M. Westaway, Ashley Barnes et al. · Neurogastroenterology & Motility · 2009 · 77 citations

Gastrointestinal Pharmacology, Gastroenterology, Pharmacotherapy +16

Potent, Selective, and CNS-Penetrant Tetrasubstituted Cyclopropane Class IIa Histone Deacetylase (HDAC) Inhibitors

Christopher A. Luckhurst, Perla Breccia, Andrew J. Stott et al. · ACS Medicinal Chemistry Letters · 2015 · 53 citations · Full text

Medicinal Chemistry, Heterocyclic, Biochemistry +13

Development and characterization of a CNS-penetrant benzhydryl hydroxamic acid class IIa histone deacetylase inhibitor

Christopher A. Luckhurst, Omar Aziz, Vahri Beaumont et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 45 citations

Biochemistry, Medicine, Natural Sciences +5