Concepedia

Host Defense Modulation

Host Defense Modulation is a biological mechanism that alters the activity or responsiveness of an organism's immune system to mitigate the impact of concurrent pathogenic infections, distinguishing it from direct pathogen-targeting strategies by focusing on host physiological adjustments.

819

Publications

55.6K

Citations

5K

Authors

1.2K

Institutions

Publications per year

2017–2026

222

Parents

Publications

819

Activation of Transcription Factor NF-κB Is Suppressed by Curcumin (Diferuloylmethane)

Sanjaya Singh, Bharat B. Aggarwal · Journal of Biological Chemistry · 1995 · 1.4K citations · Full text

, , +12

Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice

Jean M. Daley, Alan Thomay, Michael D. Connolly et al. · Journal of Leukocyte Biology · 2007 · 1K citations

, , +7

Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses

Chenguang Wang, Yukun Guan, Mengze Lv et al. · Immunity · 2018 · 814 citations · Full text

, , +13

Neurogenic inflammation and the peripheral nervous system in host defense and immunopathology

Isaac M. Chiu, Christian A. von Hehn, Clifford J. Woolf · Nature Neuroscience · 2012 · 663 citations · Full text

, , +16

Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts

Heike Grassmé, Verena Jendrossek, Andrea Riehle et al. · Nature Medicine · 2003 · 534 citations

, , +14

1–5 of 819

Authors

5K

  1. TV
    Tom van der Poll

    University of Amsterdam, Netherlands

    16 publications · 945 citations

    15

    h-index

  2. SF
    Sandrine Florquin

    Amsterdam UMC Location University of Amsterdam, Netherlands

    8 publications · 398 citations

    8

    h-index

  3. AF
    Alex F. de Vos

    University of Amsterdam, Netherlands

    7 publications · 271 citations

    7

    h-index

  4. JJ
    Joris J. T. H. Roelofs

    Amsterdam UMC Location University of Amsterdam, Netherlands

    6 publications · 359 citations

    6

    h-index

  5. YY
    Yasunobu Yoshikai

    Kyushu University, Japan

    5 publications · 580 citations

    5

    h-index

1–5 of 5K

Institutions

1.2K

  1. Harvard University

    Cambridge, United States

    21 h-index

    92 publications

    7.8K citations

  2. Amsterdam UMC Location University of Amsterdam

    Amsterdam, The Netherlands

    16 h-index

    67 publications

    2.8K citations

  3. University of Amsterdam

    Amsterdam, The Netherlands

    16 h-index

    88 publications

    3.4K citations

  4. Chinese Academy of Sciences

    Beijing, China

    15 h-index

    83 publications

    4.5K citations

  5. University of California, Los Angeles

    Los Angeles, United States

    14 h-index

    53 publications

    7.1K citations

  6. University of Michigan

    Ann Arbor, United States

    13 h-index

    59 publications

    4.5K citations

  7. National Institutes of Health

    Bethesda, United States

    13 h-index

    60 publications

    3.6K citations

  8. Inserm

    Paris, France

    13 h-index

    71 publications

    8.6K citations

1–8 of 1.2K

Venues

  1. The Journal of Immunology

    JI · 76 publications · 7.3K citations

    49

    h-index

  2. Infection and Immunity

    IAI · 43 publications · 2.4K citations

    29

    h-index

  3. PLoS ONE

    29 publications · 1.6K citations

    26

    h-index

  4. PubMed

    Repository · 43 publications · 2.2K citations

    25

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 23 publications · 2.2K citations

    20

    h-index

1–5