Tom van der Poll

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

Mervyn Singer, Clifford S. Deutschman, Christopher W. Seymour et al. · JAMA · 2016 · 26.3K citations · Full text

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

Thomas Vogl, Klaus Tenbrock, Stephan Ludwig et al. · Nature Medicine · 2007 · 1.4K citations

Inflammation, Toll-like Receptors, Molecular Immunology +13

Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis

Christopher Seymour, Jason Kennedy, Shu Wang et al. · JAMA · 2019 · 1.4K citations · Full text

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

Tim J. Schuijt, Jacqueline M. Lankelma, Brendon P. Scicluna et al. · Gut · 2015 · 808 citations · Full text

A guiding map for inflammation

Mihai G. Netea, Frances R. Balkwill, Michel Chonchol et al. · Nature Immunology · 2017 · 794 citations · Full text

Inflammation, Anti-inflammatory, Autoimmune Disease +7