Tom van der Poll

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

Mervyn Singer, Clifford S. Deutschman, Christopher W. Seymour et al. · JAMA · 2016 · 28K citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

Paul Bastard, Lindsey B. Rosen, Qian Zhang et al. · Science · 2020 · 2.8K citations · Full text

Life Sciences, Immunology, Infectious Diseases +14

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang, Paul Bastard, Zhiyong Liu et al. · Science · 2020 · 2.4K citations · Full text

Life Sciences, Immunology, Infectious Diseases +16

Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis

Christopher Seymour, Jason Kennedy, Shu Wang et al. · JAMA · 2019 · 1.5K citations · Full text

Veterinary Medicine, Clinical Sciences, Infectious Diseases +17

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

Thomas Vogl, Klaus Tenbrock, Stephan Ludwig et al. · Nature Medicine · 2007 · 1.4K citations

Life Sciences, Immunology, Molecular Biology +16