Concepedia

Histone Demethylation

Histone Demethylation is a post-translational modification process in which methyl groups are enzymatically removed from lysine or arginine residues on histone proteins, thereby altering chromatin structure and regulating gene expression.

1.4K

Publications

137.2K

Citations

9.7K

Authors

1.8K

Institutions

Publications per year

2017–2026

492

Parents

Publications

1.4K

Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1

Yujiang Geno Shi, Yujiang Geno Shi, Fei Lan et al. · Cell · 2004 · 4K citations · Full text

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Histone demethylation by a family of JmjC domain-containing proteins

Yu-ichi Tsukada, Jia Fang, Hediye Erdjument‐Bromage et al. · Nature · 2005 · 2.1K citations

, , +10

IDH mutation impairs histone demethylation and results in a block to cell differentiation

Chao Lü, Patrick S. Ward, Gurpreet S. Kapoor et al. · Nature · 2012 · 2K citations

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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

Elizabeth E. Cameron, Kurtis E. Bachman, Sanna Myöhänen et al. · Nature Genetics · 1999 · 1.9K citations

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LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription

Eric Metzger, Melanie Wissmann, Na Yin et al. · Nature · 2005 · 1.7K citations

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1–5 of 1.4K

Authors

9.7K

  1. CJ
    Christopher J. Schofield

    University of Oxford, United Kingdom

    36 publications · 4.6K citations

    30

    h-index

  2. AK
    Akane Kawamura

    University of Oxford, United Kingdom

    22 publications · 2.6K citations

    20

    h-index

  3. UO
    Udo Oppermann

    University of Oxford, United Kingdom

    20 publications · 2.6K citations

    20

    h-index

  4. AT
    Anthony Tumber

    University of Oxford, United Kingdom

    17 publications · 1.3K citations

    17

    h-index

  5. AM
    Andrea Mattevi

    University of Pavia, Italy

    17 publications · 2.2K citations

    16

    h-index

1–5 of 9.7K

Institutions

1.8K

  1. Harvard University

    Cambridge, United States

    42 h-index

    313 publications

    94.3K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    40 h-index

    147 publications

    41.7K citations

  3. Chinese Academy of Sciences

    Beijing, China

    38 h-index

    318 publications

    32.9K citations

  4. University of Oxford

    Oxford, United Kingdom

    35 h-index

    383 publications

    60.5K citations

  5. The University of Tokyo

    Tokyo, Japan

    31 h-index

    172 publications

    21.3K citations

  6. Johns Hopkins University

    Baltimore, United States

    29 h-index

    143 publications

    38.8K citations

  7. University of Copenhagen

    Copenhagen, Denmark

    23 h-index

    140 publications

    20.8K citations

  8. National Institutes of Health

    Bethesda, United States

    22 h-index

    131 publications

    16.8K citations

1–8 of 1.8K

Venues

  1. Journal of Biological Chemistry

    JBC · 62 publications · 6.5K citations

    41

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 37 publications · 5.2K citations

    34

    h-index

  3. PLoS ONE

    49 publications · 2.9K citations

    31

    h-index

  4. Nucleic Acids Research

    34 publications · 2K citations

    29

    h-index

  5. Nature Communications

    32 publications · 2.8K citations

    26

    h-index

1–5