Concepedia

Genotype-phenotype Landscape

Genotype-Phenotype Landscape is a theoretical framework that maps the space of possible genotypes to their corresponding phenotypic outcomes, capturing the structural and functional relationships that determine how genetic variation gives rise to phenotypic diversity.

165

Publications

11.2K

Citations

1.5K

Authors

721

Institutions

Publications per year

2017–2026

61

Variants

Genotype-phenotype Map

Parents

Publications

165

Evolutionary Trade-Offs, Pareto Optimality, and the Geometry of Phenotype Space

Oren Shoval, Hila Sheftel, Guy Shinar et al. · Science · 2012 · 700 citations

, , +16

Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq

Joseph M. Replogle, Reuben A. Saunders, Angela N. Pogson et al. · Cell · 2022 · 663 citations · Full text

, , +15

The Evolution of Genetic Architecture

Thomas F. Hansen · Annual Review of Ecology Evolution and Systematics · 2006 · 431 citations

, , +17

Genotype-phenotype relationship in Brugada syndrome: electrocardiographic features differentiate SCN5A-related patients from non–SCN5A-related patients

J SMITS, Lars Eckardt, Vincent Probst et al. · Journal of the American College of Cardiology · 2002 · 389 citations

, , +16

Mapping the Genetic Landscape of Human Cells

Max A. Horlbeck, Albert Xu, Min Wang et al. · Cell · 2018 · 347 citations · Full text

, , +14

1–5 of 165

Authors

1.5K

  1. SE
    Sebastian E. Ahnert

    University of Cambridge, United Kingdom

    5 publications · 229 citations

    5

    h-index

  2. SC
    Susanna C. Manrubia

    Centro de Astrobiología, Spain

    4 publications · 117 citations

    4

    h-index

  3. JA
    José A. Cuesta

    Universidad Carlos III de Madrid, Spain

    4 publications · 117 citations

    4

    h-index

  4. AA
    Ard A. Louis

    University of Oxford, United Kingdom

    4 publications · 277 citations

    4

    h-index

  5. SF
    Sam F. Greenbury

    Imperial College London, United Kingdom

    4 publications · 215 citations

    4

    h-index

1–5 of 1.5K

Institutions

721

  1. Harvard University

    Cambridge, United States

    11 h-index

    39 publications

    3.8K citations

  2. University of Oxford

    Oxford, United Kingdom

    9 h-index

    17 publications

    760 citations

  3. Inserm

    Paris, France

    9 h-index

    31 publications

    2.7K citations

  4. University of Cambridge

    Cambridge, United Kingdom

    8 h-index

    30 publications

    1K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    25 publications

    7.3K citations

  6. University of Zurich

    Zurich, Switzerland

    6 h-index

    10 publications

    668 citations

  7. Centro Nacional de Biotecnología

    Madrid, Spain

    6 h-index

    10 publications

    261 citations

  8. Broad Institute

    Cambridge, United States

    6 h-index

    27 publications

    1.8K citations

1–8 of 721

Venues

  1. Human Genetics

    7 publications · 461 citations

    7

    h-index

  2. PLoS ONE

    5 publications · 292 citations

    5

    h-index

  3. Journal of The Royal Society Interface

    5 publications · 200 citations

    5

    h-index

  4. Nature Communications

    4 publications · 241 citations

    4

    h-index

  5. Cell

    3 publications · 1.2K citations

    3

    h-index

1–5