Concepedia

Genotype-phenotype Coupling

Genotype-Phenotype Coupling is a foundational principle in directed evolution that establishes a direct and heritable relationship between a genetic variant (genotype) and its corresponding functional expression (phenotype), enabling the selection of desired traits based on measurable biological activity.

686

Publications

56.8K

Citations

3.5K

Authors

1.1K

Institutions

Publications per year

2017–2026

145

Variants

Genotype Phenotype Coupling

Parents

Children

Publications

686

GENOTYPE-ENVIRONMENT INTERACTION AND THE EVOLUTION OF PHENOTYPIC PLASTICITY

Sara Via, Russell Lande · Evolution · 1985 · 2K citations

, , +13

The Drosophila melanogaster Genetic Reference Panel

Trudy F. C. Mackay, Stephen Richards, Eric A. Stone et al. · Nature · 2012 · 1.9K citations · Full text

, , +17

Selfish genes, the phenotype paradigm and genome evolution

W. Ford Doolittle, Carmen Sapienza · Nature · 1980 · 1.8K citations

, , +13

The genetic architecture of type 2 diabetes

Christian Fuchsberger, Jason Flannick, Tanya M. Teslovich et al. · Nature · 2016 · 1.1K citations · Full text

, , +14

Evolution of the genetic apparatus

Leslie E. Orgel · Journal of Molecular Biology · 1968 · 1K citations

, , +12

1–5 of 686

Authors

3.5K

  1. AW
    Andreas Wagner

    University of Zurich, Switzerland

    15 publications · 1.8K citations

    15

    h-index

  2. RR
    Robert R. H. Anholt

    North Carolina State University, United States

    11 publications · 3K citations

    11

    h-index

  3. AB
    Arne B. Gjuvsland

    Norwegian University of Life Sciences, Norway

    8 publications · 292 citations

    8

    h-index

  4. TF
    Trudy F. C. Mackay

    North Carolina State University, United States

    7 publications · 2.3K citations

    7

    h-index

  5. SE
    Sebastian E. Ahnert

    University of Cambridge, United Kingdom

    7 publications · 342 citations

    7

    h-index

1–5 of 3.5K

Institutions

1.1K

  1. Stanford University

    Stanford, United States

    18 h-index

    47 publications

    8.8K citations

  2. University of Oxford

    Oxford, United Kingdom

    17 h-index

    102 publications

    64K citations

  3. University of Cambridge

    Cambridge, United Kingdom

    17 h-index

    72 publications

    29.8K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    17 h-index

    58 publications

    9K citations

  5. North Carolina State University

    Raleigh, United States

    17 h-index

    85 publications

    36.7K citations

  6. Harvard University

    Cambridge, United States

    16 h-index

    78 publications

    37.7K citations

  7. Duke University

    Durham, United States

    15 h-index

    32 publications

    2.2K citations

  8. Santa Fe Institute

    Santa Fe, United States

    14 h-index

    20 publications

    2.5K citations

1–8 of 1.1K

Venues

  1. Genetics

    42 publications · 2.9K citations

    27

    h-index

  2. Evolution

    22 publications · 4.2K citations

    20

    h-index

  3. The American Journal of Human Genetics

    AJHG · 16 publications · 1.7K citations

    16

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 15 publications · 1.4K citations

    15

    h-index

  5. PLoS Computational Biology

    13 publications · 525 citations

    12

    h-index

1–5