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Cell

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Cell

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Cell

EngineeringGeneticsTranscriptomics TechnologyTrajectory AnalysisTranscriptional Regulation +15

Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors

Joseph M. Replogle, Jessica L. Bonnar, Angela N. Pogson, +15

eLife

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MTCH2 is a mitochondrial outer membrane protein insertase

Alina Guna, Taylor A. Stevens, Alison J. Inglis, +11

Science

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Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq

Joseph M. Replogle, Reuben A. Saunders, Angela N. Pogson, +14

GeneticsMolecular GeneticsGenomicsTranscriptional RegulationGenotype-phenotype Association +19

DNA-guided transcription factor cooperativity shapes face and limb mesenchyme

Seungsoo Kim, Ekaterina Morgunova, Sahin Naqvi, +9

Cell

CRISPR–Cas9 screens reveal regulators of ageing in neural stem cells

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Nature

Ubiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion

Fernando Rodríguez-Pérez, Andrew G. Manford, Angela N. Pogson, +3

Developmental Cell

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