Joseph M. Replogle

Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

Nikolaos A. Patsopoulos, Sergio E. Baranzini, Adam Santaniello et al. · Science · 2019 · 1.3K citations · Full text

Immunology, Extended Mhc, Innate Immunity +16

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus

James Bentham, David Morris, Deborah S. Cunninghame Graham et al. · Nature Genetics · 2015 · 1K citations · Full text

Aberrant Regulation, Immunogenetics, Autoimmune Disease +11

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

Philip L. De Jager, Gyan Srivastava, Katie Lunnon et al. · Nature Neuroscience · 2014 · 974 citations · Full text

Alzheimer's Disease, Epigenetic Change, Genetics +12

Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing

James K. Nuñez, Chen Jin, Greg C. Pommier et al. · Cell · 2021 · 696 citations · Full text

Chromatin, Crispr-based Epigenome Editing, Genetics +5

Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq

Joseph M. Replogle, Reuben A. Saunders, Angela N. Pogson et al. · Cell · 2022 · 581 citations · Full text