Reuben A. Saunders

Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq

Joseph M. Replogle, Reuben A. Saunders, Angela N. Pogson et al. · Cell · 2022 · 581 citations · Full text

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

Michael Schoof, Bryan Faust, Reuben A. Saunders et al. · Science · 2020 · 462 citations · Full text

Materials Science, Trivalent Nanobody, Spike Protein +10

A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response

Niko Amin-Wetzel, Reuben A. Saunders, Maarten J. Kamphuis et al. · Cell · 2017 · 250 citations · Full text

Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs

Marco Jost, Daniel A. Santos, Reuben A. Saunders et al. · Nature Biotechnology · 2020 · 169 citations · Full text

Off-target Effect, Engineering, Genetics +10

Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq

Joseph M. Replogle, Reuben A. Saunders, Angela N. Pogson et al. · 2021 · 78 citations · Full text

Genetics, Molecular Genetics, Genomics +21