Concepedia

Dose-dependent Bioavailability

Dose-Dependent Bioavailability is a pharmacokinetic phenomenon in which the systemic exposure of a drug changes disproportionately with alterations in administered dose, distinguished from dose-independent bioavailability by its reliance on nonlinear absorption, distribution, metabolism, or excretion processes.

77

Publications

3.8K

Citations

452

Authors

153

Institutions

Publications per year

2017–2026

19

Parents

Publications

77

Iron absorption in man: ascorbic acid and dose-dependent inhibition by phytate

Leif Hallberg, Mats Brune, L Rossander · American Journal of Clinical Nutrition · 1989 · 622 citations

, , +16

Clinical pharmacokinetics of gabapentin.

Michael J. McLean · PubMed · 1994 · 263 citations

, , +16

Transport of celiprolol across human intestinal epithelial (Caco‐2) cells: mediation of secretion by multiple transporters including P‐glycoprotein

Johan Karlsson, Shiu‐Ming Kuo, John A. Ziemniak et al. · British Journal of Pharmacology · 1993 · 180 citations · Full text

, , +17

Pharmacokinetics and oral bioavailability of exogenous melatonin in preclinical animal models and clinical implications

Krishnaswamy Yeleswaram, Lee G. McLaughlin, Jay O. Knipe et al. · Journal of Pineal Research · 1997 · 170 citations

, , +13

Dose‐dependent utilisation of casein‐linked lysinoalanine,<i> N</i>(epsilon)‐fructoselysine and<i> N</i>(epsilon)‐carboxymethyllysine in rats

Veronika Somoza, Elisabeth Wenzel, Carola Weiß et al. · Molecular Nutrition & Food Research · 2006 · 125 citations

, , +17

1–5 of 77

Authors

452

  1. JD
    Jürgen Drewe

    University Hospital of Basel, Switzerland

    2 publications · 88 citations

    2

    h-index

  2. KB
    Kevin Beaumont

    Pfizer (United Kingdom), United Kingdom

    1 publications · 29 citations

    1

    h-index

  3. RC
    Rajesh Chavan

    Wockhardt Hospitals, India

    1 publications · 13 citations

    1

    h-index

  4. FL
    Fangbiao Li

    Central South University, China

    1 publications · 28 citations

    1

    h-index

  5. GM
    Giovanni Merlino

    University of Udine, Italy

    1 publications · 10 citations

    1

    h-index

1–5 of 452

Institutions

153

  1. Universidad de Montevideo

    Montevideo, Uruguay

    2 h-index

    4 publications

    59 citations

  2. Bristol-Myers Squibb (United States)

    New York, United States

    2 h-index

    36 publications

    1.8K citations

  3. University of Florida

    Gainesville, United States

    2 h-index

    5 publications

    98 citations

  4. Uppsala University

    Uppsala, Sweden

    2 h-index

    3 publications

    370 citations

  5. Oregon State University

    Corvallis, United States

    2 h-index

    11 publications

    400 citations

  6. King Saud University

    Riyadh, Saudi Arabia

    2 h-index

    3 publications

    70 citations

  7. University at Buffalo, State University of New York

    Buffalo, United States

    2 h-index

    3 publications

    310 citations

  8. Pfizer (United States)

    New York, United States

    2 h-index

    7 publications

    161 citations

1–8 of 153

Venues

  1. PubMed

    Repository · 9 publications · 401 citations

    9

    h-index

  2. Clinical Pharmacology & Therapeutics

    CPT · 4 publications · 251 citations

    4

    h-index

  3. Clinical Pharmacokinetics

    3 publications · 156 citations

    3

    h-index

  4. Drug Metabolism and Disposition

    3 publications · 62 citations

    3

    h-index

  5. Biopharmaceutics & Drug Disposition

    2 publications · 37 citations

    2

    h-index

1–5