Concepedia

Cancer Initiation

Cancer Initiation is the irreversible genetic alteration in a cell, typically caused by carcinogenic exposure, that marks the first step in carcinogenesis by conferring a latent neoplastic potential.

1.3K

Publications

114.3K

Citations

7.4K

Authors

1.6K

Institutions

Publications per year

2017–2026

219

Parents

Children

Publications

1.3K

Identification and expansion of human colon-cancer-initiating cells

Lucia Ricci‐Vitiani, Dario Lombardi, Emanuela Pilozzi et al. · Nature · 2006 · 4K citations

, , +12

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Yurij Ionov, Miguel A. Peinado, Sergei Malkhosyan et al. · Nature · 1993 · 2.7K citations

, , +17

Isolation and <i>In vitro</i> Propagation of Tumorigenic Breast Cancer Cells with Stem/Progenitor Cell Properties

Dario Ponti, Aurora Costa, Nadia Zaffaroni et al. · Cancer Research · 2005 · 1.7K citations · Full text

, , +17

The translational landscape of mTOR signalling steers cancer initiation and metastasis

Andrew C. Hsieh, Yi Liu, Merritt P. Edlind et al. · Nature · 2012 · 1.4K citations

, , +14

Mutator phenotype may be required for multistage carcinogenesis.

L A Loeb · PubMed · 1991 · 1.3K citations

, , +11

1–5 of 1.3K

Authors

7.4K

  1. SH
    Suresh H. Moolgavkar

    Fred Hutch Cancer Center, United States

    11 publications · 1.1K citations

    11

    h-index

  2. EF
    Emmanuel Farber

    University of Toronto, Canada

    10 publications · 1.6K citations

    10

    h-index

  3. WJ
    William J. Muller

    McGill University, Canada

    9 publications · 1.2K citations

    9

    h-index

  4. RD
    Robert D. Cardiff

    University of California, Davis, United States

    8 publications · 966 citations

    8

    h-index

  5. CB
    Cédric Blanpain

    Université Libre de Bruxelles, Belgium

    7 publications · 1.5K citations

    7

    h-index

1–5 of 7.4K

Institutions

1.6K

  1. Harvard University

    Cambridge, United States

    38 h-index

    172 publications

    40K citations

  2. National Cancer Institute

    Bethesda, United States

    33 h-index

    166 publications

    25K citations

  3. National Institutes of Health

    Bethesda, United States

    26 h-index

    104 publications

    18.4K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    25 h-index

    78 publications

    28.3K citations

  5. Dana-Farber Cancer Institute

    Boston, United States

    23 h-index

    118 publications

    23.7K citations

  6. German Cancer Research Center

    Heidelberg, Germany

    22 h-index

    99 publications

    9.6K citations

  7. The University of Texas MD Anderson Cancer Center

    Houston, United States

    22 h-index

    97 publications

    8.5K citations

  8. University of Toronto

    Toronto, Canada

    22 h-index

    91 publications

    10.4K citations

1–8 of 1.6K

Venues

  1. PubMed

    Repository · 139 publications · 10.4K citations

    51

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 53 publications · 8.4K citations

    43

    h-index

  3. Oncogene

    66 publications · 4.7K citations

    41

    h-index

  4. Nature

    27 publications · 14.2K citations

    25

    h-index

  5. Cancer Research

    33 publications · 4.8K citations

    25

    h-index

1–5